Diffusionless fluid transport and routing using novel microfluidic devices. Page: 3 of 36
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SAND2006-7620
Unlimited Release
Printed November 2006
Diffusionless fluid transport and routing using novel microfluidic
devices
David S. Reichmuth, Louise M. Barrett, and Renee Shediac
Microfluidics Department
Sandia National Laboratories
P.O. Box 969
Livermore, California 94550-MS9291
ABSTRACT
Microfluidic devices have been proposed for "Lab-on-a-Chip" applications for nearly a
decade. Despite the unquestionable promise of these devices to allow rapid, sensitive
and portable biochemical analysis, few practical devices exist. It is often difficult to
adapt current laboratory techniques to the microscale because bench-top methods use
discrete liquid volumes, while most current microfluidic devices employ streams of
liquid confined in a branching network of micron-scale channels. The goal of this
research was to use two phase liquid flows, creating discrete packets of liquid. Once
divided into discrete packets, the packets can be moved controllably within the
microchannels without loss of material. Each packet is equivalent to a minute test tube,
holding a fraction from a separation or an aliquot to be reacted.
We report on the fabrication of glass and PDMS (polydimethylsiloxane) devices that
create and store packets.
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Barrett, Louise Mary; Shediac, Renee & Reichmuth, David S. Diffusionless fluid transport and routing using novel microfluidic devices., report, November 1, 2006; United States. (https://digital.library.unt.edu/ark:/67531/metadc932844/m1/3/: accessed April 25, 2024), University of North Texas Libraries, UNT Digital Library, https://digital.library.unt.edu; crediting UNT Libraries Government Documents Department.