Breast ultrasound tomography with total-variation regularization

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Breast ultrasound tomography is a rapidly developing imaging modality that has the potential to impact breast cancer screening and diagnosis. A new ultrasound breast imaging device (CURE) with a ring array of transducers has been designed and built at Karmanos Cancer Institute, which acquires both reflection and transmission ultrasound signals. To extract the sound-speed information from the breast data acquired by CURE, we have developed an iterative sound-speed image reconstruction algorithm for breast ultrasound transmission tomography based on total-variation (TV) minimization. We investigate applicability of the TV tomography algorithm using in vivo ultrasound breast data from 61 patients, and compare ... continued below

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Huang, Lianjie; Li, Cuiping & Duric, Neb January 1, 2009.

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Breast ultrasound tomography is a rapidly developing imaging modality that has the potential to impact breast cancer screening and diagnosis. A new ultrasound breast imaging device (CURE) with a ring array of transducers has been designed and built at Karmanos Cancer Institute, which acquires both reflection and transmission ultrasound signals. To extract the sound-speed information from the breast data acquired by CURE, we have developed an iterative sound-speed image reconstruction algorithm for breast ultrasound transmission tomography based on total-variation (TV) minimization. We investigate applicability of the TV tomography algorithm using in vivo ultrasound breast data from 61 patients, and compare the results with those obtained using the Tikhonov regularization method. We demonstrate that, compared to the Tikhonov regularization scheme, the TV regularization method significantly improves image quality, resulting in sound-speed tomography images with sharp (preserved) edges of abnormalities and few artifacts.

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  • 2009 SPIE Medical Imaging ; February 7, 2009 ; Orlando, FL

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  • Report No.: LA-UR-09-00407
  • Report No.: LA-UR-09-407
  • Grant Number: AC52-06NA25396
  • Office of Scientific & Technical Information Report Number: 956546
  • Archival Resource Key: ark:/67531/metadc927701

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  • January 1, 2009

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  • Nov. 13, 2016, 7:26 p.m.

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  • Dec. 9, 2016, 10:44 p.m.

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Huang, Lianjie; Li, Cuiping & Duric, Neb. Breast ultrasound tomography with total-variation regularization, article, January 1, 2009; [New Mexico]. (digital.library.unt.edu/ark:/67531/metadc927701/: accessed October 17, 2017), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT Libraries Government Documents Department.