Cyclotron Produced Radionuclides for Diagnosis and Therapy of Human Neoplasms

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This project funded since 1986 serves as a core project for cancer research throughout MSKCC, producing key radiotracers as well as basic knowledge about thel physics of radiation decay and imaging, for nuclear medicine applications to cancer diagnosis and therapy. In recent years this research application has broadened to include experiments intended to lead to an improved understanding of cancer biology and into the discovery and testing of new cancer drugs. Advances in immune based radiotargeting form the basis for this project. Both antibody and cellular based immune targeting methods have been explored. The multi-step targeting methodologies (MST) developed by ... continued below

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MD, Steven Larson September 21, 2009.

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This report is part of the collection entitled: Office of Scientific & Technical Information Technical Reports and was provided by UNT Libraries Government Documents Department to Digital Library, a digital repository hosted by the UNT Libraries. It has been viewed 45 times . More information about this report can be viewed below.

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Description

This project funded since 1986 serves as a core project for cancer research throughout MSKCC, producing key radiotracers as well as basic knowledge about thel physics of radiation decay and imaging, for nuclear medicine applications to cancer diagnosis and therapy. In recent years this research application has broadened to include experiments intended to lead to an improved understanding of cancer biology and into the discovery and testing of new cancer drugs. Advances in immune based radiotargeting form the basis for this project. Both antibody and cellular based immune targeting methods have been explored. The multi-step targeting methodologies (MST) developed by NeoRex (Seattle,Washington), have been adapted for use with positron emitting isotopes and PET allowing the quantification and optimization of targeted delivery. In addition, novel methods for radiolabeling immune T-cells with PET tracers have advanced our ability to track these cells of prolonged period of time.

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  • Report No.: DOE/ER/60407
  • Grant Number: FG02-86ER60407
  • DOI: 10.2172/964282 | External Link
  • Office of Scientific & Technical Information Report Number: 964282
  • Archival Resource Key: ark:/67531/metadc927406

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Office of Scientific & Technical Information Technical Reports

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  • September 21, 2009

Added to The UNT Digital Library

  • Nov. 13, 2016, 7:26 p.m.

Description Last Updated

  • Nov. 23, 2016, 12:17 p.m.

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MD, Steven Larson. Cyclotron Produced Radionuclides for Diagnosis and Therapy of Human Neoplasms, report, September 21, 2009; United States. (digital.library.unt.edu/ark:/67531/metadc927406/: accessed July 19, 2018), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT Libraries Government Documents Department.