Protein Microarrays--Without a Trace

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Many experimental approaches in biology and biophysics, as well as applications in diagnosis and drug discovery, require proteins to be immobilized on solid supports. Protein microarrays, for example, provide a high-throughput format to study biomolecular interactions. The technique employed for protein immobilization is a key to the success of these applications. Recent biochemical developments are allowing, for the first time, the selective and traceless immobilization of proteins generated by cell-free systems without the need for purification and/or reconcentration prior to the immobilization step.

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PDF-file: 9 pages; size: 1.5 Mbytes

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Camarero, J A April 5, 2007.

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Many experimental approaches in biology and biophysics, as well as applications in diagnosis and drug discovery, require proteins to be immobilized on solid supports. Protein microarrays, for example, provide a high-throughput format to study biomolecular interactions. The technique employed for protein immobilization is a key to the success of these applications. Recent biochemical developments are allowing, for the first time, the selective and traceless immobilization of proteins generated by cell-free systems without the need for purification and/or reconcentration prior to the immobilization step.

Physical Description

PDF-file: 9 pages; size: 1.5 Mbytes

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  • Journal Name: BIOforum Europe, vol. 5, no. 1, June 1, 2007, pp. 30-33; Journal Volume: 5; Journal Issue: 1

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  • Report No.: UCRL-JRNL-230183
  • Grant Number: W-7405-ENG-48
  • Office of Scientific & Technical Information Report Number: 940883
  • Archival Resource Key: ark:/67531/metadc901586

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Office of Scientific & Technical Information Technical Reports

Reports, articles and other documents harvested from the Office of Scientific and Technical Information.

Office of Scientific and Technical Information (OSTI) is the Department of Energy (DOE) office that collects, preserves, and disseminates DOE-sponsored research and development (R&D) results that are the outcomes of R&D projects or other funded activities at DOE labs and facilities nationwide and grantees at universities and other institutions.

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  • April 5, 2007

Added to The UNT Digital Library

  • Sept. 27, 2016, 1:39 a.m.

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  • Dec. 9, 2016, 6:52 p.m.

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Camarero, J A. Protein Microarrays--Without a Trace, article, April 5, 2007; Livermore, California. (digital.library.unt.edu/ark:/67531/metadc901586/: accessed October 21, 2017), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT Libraries Government Documents Department.