The mechanics of soft biological composites.

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Description

Biological tissues are uniquely structured materials with technologically appealing properties. Soft tissues such as skin, are constructed from a composite of strong fibrils and fluid-like matrix components. This was the first coordinated experimental/modeling project at Sandia or in the open literature to consider the mechanics of micromechanically-based anisotropy and viscoelasticity of soft biological tissues. We have exploited and applied Sandia's expertise in experimentation and mechanics modeling to better elucidate the behavior of collagen fibril-reinforced soft tissues. The purpose of this project was to provide a detailed understanding of the deformation of ocular tissues, specifically the highly structured skin-like tissue in ... continued below

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122 p.

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Nguyen, Thao D. (Sandia National Laboratories, Livermore, CA); Grazier, John Mark; Boyce, Brad Lee & Jones, Reese E. (Sandia National Laboratories, Livermore, CA) October 1, 2007.

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Description

Biological tissues are uniquely structured materials with technologically appealing properties. Soft tissues such as skin, are constructed from a composite of strong fibrils and fluid-like matrix components. This was the first coordinated experimental/modeling project at Sandia or in the open literature to consider the mechanics of micromechanically-based anisotropy and viscoelasticity of soft biological tissues. We have exploited and applied Sandia's expertise in experimentation and mechanics modeling to better elucidate the behavior of collagen fibril-reinforced soft tissues. The purpose of this project was to provide a detailed understanding of the deformation of ocular tissues, specifically the highly structured skin-like tissue in the cornea. This discovery improved our knowledge of soft/complex materials testing and modeling. It also provided insight into the way that cornea tissue is bio-engineered such that under physiologically-relevant conditions it has a unique set of properties which enhance functionality. These results also provide insight into how non-physiologic loading conditions, such as corrective surgeries, may push the cornea outside of its natural design window, resulting in unexpected non-linear responses. Furthermore, this project created a clearer understanding of the mechanics of soft tissues that could lead to bio-inspired materials, such as highly supple and impact resistant body armor, and improve our design of human-machine interfaces, such as micro-electrical-mechanical (MEMS) based prosthetics.

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122 p.

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  • Report No.: SAND2007-6191
  • Grant Number: AC04-94AL85000
  • DOI: 10.2172/922773 | External Link
  • Office of Scientific & Technical Information Report Number: 922773
  • Archival Resource Key: ark:/67531/metadc899964

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Office of Scientific & Technical Information Technical Reports

Reports, articles and other documents harvested from the Office of Scientific and Technical Information.

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Creation Date

  • October 1, 2007

Added to The UNT Digital Library

  • Sept. 27, 2016, 1:39 a.m.

Description Last Updated

  • Dec. 7, 2016, 5:37 p.m.

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Nguyen, Thao D. (Sandia National Laboratories, Livermore, CA); Grazier, John Mark; Boyce, Brad Lee & Jones, Reese E. (Sandia National Laboratories, Livermore, CA). The mechanics of soft biological composites., report, October 1, 2007; United States. (digital.library.unt.edu/ark:/67531/metadc899964/: accessed July 15, 2018), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT Libraries Government Documents Department.