Enzymatic Ligation Creates Discrete Multi-Nanoparticle Building Blocks for Self-Assembly

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Description

Enzymatic ligation of discrete nanoparticle?DNA conjugates creates nanoparticle dimer and trimer structures in which the nanoparticles are linked by single-stranded DNA, rather than double-stranded DNA as in previous experiments. Ligation is verified by agarose gel and small-angle X-ray scattering. This capability is utilized in two ways: first to create a new class of multiparticle building blocks for nanoscale self-assembly; second to develop a system which can amplify a population of discrete nanoparticle assemblies.

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Claridge, Shelley A.; Mastroianni, Alexander J.; Au, Yeung B.; Liang, Huiyang W.; Micheel, Christine M.; Frechet, Jean M.J. et al. May 27, 2008.

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Enzymatic ligation of discrete nanoparticle?DNA conjugates creates nanoparticle dimer and trimer structures in which the nanoparticles are linked by single-stranded DNA, rather than double-stranded DNA as in previous experiments. Ligation is verified by agarose gel and small-angle X-ray scattering. This capability is utilized in two ways: first to create a new class of multiparticle building blocks for nanoscale self-assembly; second to develop a system which can amplify a population of discrete nanoparticle assemblies.

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  • Journal Name: Journal of the American Chemical Society; Journal Volume: 130; Related Information: Journal Publication Date: July 23, 2008

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  • Report No.: LBNL-1171E
  • Grant Number: DE-AC02-05CH11231
  • Office of Scientific & Technical Information Report Number: 941057
  • Archival Resource Key: ark:/67531/metadc899189

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  • May 27, 2008

Added to The UNT Digital Library

  • Sept. 27, 2016, 1:39 a.m.

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  • Sept. 30, 2016, 6:28 p.m.

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Claridge, Shelley A.; Mastroianni, Alexander J.; Au, Yeung B.; Liang, Huiyang W.; Micheel, Christine M.; Frechet, Jean M.J. et al. Enzymatic Ligation Creates Discrete Multi-Nanoparticle Building Blocks for Self-Assembly, article, May 27, 2008; Berkeley, California. (digital.library.unt.edu/ark:/67531/metadc899189/: accessed August 18, 2017), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT Libraries Government Documents Department.