CARBOXYLATIONS AND DECARBOXYLATIONS

PDF Version Also Available for Download.

Description

A brief survey of decarboxylation reactions and carboxylation reactions that are known or presumed in biological systems will be presented. While a considerable number of amino acid decarboxylations are known, their mechanisms will not be included in the present discussion but will be reserved for a later paper in the symposium. The remaining decarboxylation reactions may be subdivided into oxidative and nonoxidative decarboxylations. In most cases, these reactions are practically irreversible except when coupled with suitable energy-yielding systems. The carboxylation reactions which are useful in the formation of carbon-carbon bonds in biological systems seem to fall into two or three ... continued below

Physical Description

49 p.

Creation Information

Calvin, Melvin & Pon, Ning G. April 21, 1959.

Context

This report is part of the collection entitled: Office of Scientific & Technical Information Technical Reports and was provided by UNT Libraries Government Documents Department to Digital Library, a digital repository hosted by the UNT Libraries. More information about this report can be viewed below.

Who

People and organizations associated with either the creation of this report or its content.

Publisher

Provided By

UNT Libraries Government Documents Department

Serving as both a federal and a state depository library, the UNT Libraries Government Documents Department maintains millions of items in a variety of formats. The department is a member of the FDLP Content Partnerships Program and an Affiliated Archive of the National Archives.

Contact Us

What

Descriptive information to help identify this report. Follow the links below to find similar items on the Digital Library.

Description

A brief survey of decarboxylation reactions and carboxylation reactions that are known or presumed in biological systems will be presented. While a considerable number of amino acid decarboxylations are known, their mechanisms will not be included in the present discussion but will be reserved for a later paper in the symposium. The remaining decarboxylation reactions may be subdivided into oxidative and nonoxidative decarboxylations. In most cases, these reactions are practically irreversible except when coupled with suitable energy-yielding systems. The carboxylation reactions which are useful in the formation of carbon-carbon bonds in biological systems seem to fall into two or three groups: those which exhibit an apparent ATP requirement, and those which exhibit a reduced pyridine nucleotide requirement, and those which exhibit no apparent ATP requirement. Of the first group at least four cases, and possibly six or seven, are known, and one interpretation of them involves the preliminary formation of 'active' carbon dioxide, generally in the form of a carbonic acid-phosphoric acid anhydride. Those exhibiting no apparent ATP requirement seem to be susceptible to classifications as enol carboxylations in which the energy level of the substrate compound is high, rather than that of the carbon dioxide. There appear to be at least three examples of this latter type known, amongs them being the carboxy-dismutase reaction of ribulose diphosphate with carbon dioxide.

Physical Description

49 p.

Language

Item Type

Identifier

Unique identifying numbers for this report in the Digital Library or other systems.

  • Report No.: UCRL--8732
  • Grant Number: DE-AC02-05CH11231
  • DOI: 10.2172/919681 | External Link
  • Office of Scientific & Technical Information Report Number: 919681
  • Archival Resource Key: ark:/67531/metadc896532

Collections

This report is part of the following collection of related materials.

Office of Scientific & Technical Information Technical Reports

What responsibilities do I have when using this report?

When

Dates and time periods associated with this report.

Creation Date

  • April 21, 1959

Added to The UNT Digital Library

  • Sept. 27, 2016, 1:39 a.m.

Description Last Updated

  • Nov. 3, 2016, 7:49 p.m.

Usage Statistics

When was this report last used?

Yesterday: 0
Past 30 days: 0
Total Uses: 1

Interact With This Report

Here are some suggestions for what to do next.

Start Reading

PDF Version Also Available for Download.

Citations, Rights, Re-Use

Calvin, Melvin & Pon, Ning G. CARBOXYLATIONS AND DECARBOXYLATIONS, report, April 21, 1959; Berkeley, California. (digital.library.unt.edu/ark:/67531/metadc896532/: accessed September 20, 2017), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT Libraries Government Documents Department.