Biocompatible self-assembly of nano-materials for Bio-MEMS and insect reconnaissance.

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Description

This report summarizes the development of new biocompatible self-assembly procedures enabling the immobilization of genetically engineered cells in a compact, self-sustaining, remotely addressable sensor platform. We used evaporation induced self-assembly (EISA) to immobilize cells within periodic silica nanostructures, characterized by unimodal pore sizes and pore connectivity, that can be patterned using ink-jet printing or photo patterning. We constructed cell lines for the expression of fluorescent proteins and induced reporter protein expression in immobilized cells. We investigated the role of the abiotic/biotic interface during cell-mediated self-assembly of synthetic materials.

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23 p.

Creation Information

Brozik, Susan Marie; Cesarano, Joseph, III; Brinker, C. Jeffrey; Dunphy, Darren Robert; Sinclair, Michael B.; Manginell, Monica et al. December 1, 2003.

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Description

This report summarizes the development of new biocompatible self-assembly procedures enabling the immobilization of genetically engineered cells in a compact, self-sustaining, remotely addressable sensor platform. We used evaporation induced self-assembly (EISA) to immobilize cells within periodic silica nanostructures, characterized by unimodal pore sizes and pore connectivity, that can be patterned using ink-jet printing or photo patterning. We constructed cell lines for the expression of fluorescent proteins and induced reporter protein expression in immobilized cells. We investigated the role of the abiotic/biotic interface during cell-mediated self-assembly of synthetic materials.

Physical Description

23 p.

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  • Report No.: SAND2003-4075
  • Grant Number: AC04-94AL85000
  • DOI: 10.2172/918382 | External Link
  • Office of Scientific & Technical Information Report Number: 918382
  • Archival Resource Key: ark:/67531/metadc887105

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Office of Scientific & Technical Information Technical Reports

Reports, articles and other documents harvested from the Office of Scientific and Technical Information.

Office of Scientific and Technical Information (OSTI) is the Department of Energy (DOE) office that collects, preserves, and disseminates DOE-sponsored research and development (R&D) results that are the outcomes of R&D projects or other funded activities at DOE labs and facilities nationwide and grantees at universities and other institutions.

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Creation Date

  • December 1, 2003

Added to The UNT Digital Library

  • Sept. 22, 2016, 2:13 a.m.

Description Last Updated

  • Dec. 9, 2016, 3:27 p.m.

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Brozik, Susan Marie; Cesarano, Joseph, III; Brinker, C. Jeffrey; Dunphy, Darren Robert; Sinclair, Michael B.; Manginell, Monica et al. Biocompatible self-assembly of nano-materials for Bio-MEMS and insect reconnaissance., report, December 1, 2003; United States. (digital.library.unt.edu/ark:/67531/metadc887105/: accessed October 18, 2017), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT Libraries Government Documents Department.