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DOE AWARD/CONTRACT NUMBER: DE-FG02-02ER63464
STI PRODUCT TITLE: Genetics and Common Disorders: Implications for Primary
Care and Public Health Providers
PRINCIPAL INVESTIGATORS: McInerney, Joseph D.; Greendale, Karen
AUTHORS: McInerney, Joseph D.; Greendale, Karen; Peay, Holly L., et al.
We developed this program for primary care providers (PCPs) and public health
professionals (PHPs) who are interested in increasing their understanding of the genetics
of common chronic diseases and of the implications of genetics and genomics for their
fields. The program differs from virtually all previous educational efforts in genetics for
health professionals in that it focuses on the genetics of common chronic disease and on
the broad principles that emerge when one views disease from the perspectives of
variation and individuality, which are at the heart of thinking genetically. The CD-ROM
introduces users to content that will improve their understanding of topics such as:
- A framework for genetics and common disease;
- Basic information on genetics, genomics, genetic medicine, and public health
genetics, all in the context of common chronic disease;
- The status of research on genetic contributions to specific common diseases,
including a review of research methods;
- Genetic/environmental interaction as the new "central dogma" of public health
- The importance of taking and analyzing a family history;
- The likely impact of potential gene discovery and genetic testing on genetic
counseling and risk assessment and on the practices of PCPs and PHPs;
- Stratification of populations into low-, moderate-, and high-risk categories;
- The potential role of PCPs and PHPs in identifying high-risk individuals and
families, in providing limited genetics services, and in referring to clinical
genetics specialists; the potential for standard referral algorithms;
- Implications of genetic insights for diagnosis and treatment;
- Ethical, legal, and social issues that arise from genetic testing for common chronic
- Specific prevention strategies based on understanding of genetics and genetic/
The interactive content - developed by experts in genetics, primary care, and public
health - is organized around two case studies designed to appeal to primary care
providers (thrombophilia) and public health professionals (development of a screening
grogram for colorectal cancer).
NCHPEG has distributed more than 10,000 copies of the CD-ROM to NCHPEG member
organizations and to other organizations and individuals in response to requests. The
program also is available at www.nchpeg.org, or from NCHPEG, at 3260 West Joppa
Road, Lutherville, Maryland.
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McInerney, Joseph D.; Greendale, Karen & Peay, Holly L. Genetics and Common Disorders: Implications for Primary Care and Public Health Providers, text, June 1, 2005; United States. (digital.library.unt.edu/ark:/67531/metadc884832/m1/1/: accessed January 23, 2019), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT Libraries Government Documents Department.