MOLECULAR MECHANISM OF URANIUM REDUCTION BY CLOSTRIDIA AND ITS MANIPULATION. Metadata

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Title

  • Main Title MOLECULAR MECHANISM OF URANIUM REDUCTION BY CLOSTRIDIA AND ITS MANIPULATION.

Creator

  • Author: FRANCIS, A.J.
    Creator Type: Personal
  • Author: GAO, W.
    Creator Type: Personal
  • Author: CHIDAMBARAM, D.
    Creator Type: Personal
  • Author: DODGE, C.J.
    Creator Type: Personal

Contributor

  • Sponsor: DOE/SC AND ERSP
    Contributor Type: Organization

Publisher

  • Name: Brookhaven National Laboratory
    Place of Publication: [Upton, New York]

Date

  • Creation: 2006-11-16

Language

  • English

Description

  • Content Description: This research addresses the need for detailed studies of the enzymatic mechanisms for reduction of radionuclides and/or metals by fermentative microorganisms. The overall objective of this research is to elucidate systematically the molecular mechanisms involved in the reduction of uranium by Clostridia. We propose to (1) determine the role of hydrogenases in uranium reduction, (2) purify the enzymes involved in uranium reduction, (3) determine the mechanisms of reduction, e.g., one or two electron transfer reactions, and (4) elucidate the genetic control of the enzymes and cellular factors involved in uranium reduction. This is a collaborative study between BNL and Stanford University involving expertise in biomolecular science, biochemistry, microbiology, and electrochemistry.
  • Physical Description: 7 pages

Subject

  • Keyword: Uranium
  • Keyword: Microorganisms
  • Keyword: Hydrogenases
  • Keyword: Enzymes
  • Keyword: Biochemistry
  • STI Subject Categories: 59 Basic Biological Sciences
  • Keyword: Electrochemistry
  • Keyword: Bnl
  • Keyword: Genetic Control
  • Keyword: Electron Transfer
  • Keyword: Radioisotopes

Collection

  • Name: Office of Scientific & Technical Information Technical Reports
    Code: OSTI

Institution

  • Name: UNT Libraries Government Documents Department
    Code: UNTGD

Resource Type

  • Report

Format

  • Text

Identifier

  • Report No.: BNL--77302-2006
  • Grant Number: DE-AC02-98CH10886
  • DOI: 10.2172/896458
  • Office of Scientific & Technical Information Report Number: 896458
  • Archival Resource Key: ark:/67531/metadc881783