Comparison of Channelized Hotelling and Human Observers inDetermining Optimum OS-EM Reconstruction Parameters for MyocardialSPECT

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The performance of the Channelized Hotelling Observer (CHO)was compared to that of human observers for determining optimumparameters for the iterative OS-EM image reconstruction method for thetask of defect detection in myocardial SPECT images. The optimumparameters were those that maximized defect detectability in the SPECTimages. Low noise, parallel SPECT projection data, with and without ananterior, inferior or lateral LV wall defect, were simulated using theMonte Carlo method. Poisson noise was added to generate noisyrealizations. Data were reconstructed using OS-EM at 1&4subsets/iteration and at 1, 3, 5, 7&9 iterations. Images wereconverted to 2D short-axis slices with integer pixel values. The CHO used3 ... continued below

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Gilland, Karen L.; Tsui, Benjamin M.W.; Qi, Yujin & Gullberg,Grant T. July 1, 2005.

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The performance of the Channelized Hotelling Observer (CHO)was compared to that of human observers for determining optimumparameters for the iterative OS-EM image reconstruction method for thetask of defect detection in myocardial SPECT images. The optimumparameters were those that maximized defect detectability in the SPECTimages. Low noise, parallel SPECT projection data, with and without ananterior, inferior or lateral LV wall defect, were simulated using theMonte Carlo method. Poisson noise was added to generate noisyrealizations. Data were reconstructed using OS-EM at 1&4subsets/iteration and at 1, 3, 5, 7&9 iterations. Images wereconverted to 2D short-axis slices with integer pixel values. The CHO used3 radially-symmetric, 2D channels, with varying levels of internalobserver noise. For each parameter setting, 600 defect-present and 600defect-absent image vectors were used to calculate the detectabilityindex (dA). The human observers rated the likelihood that a defect waspresent in a specified location. For each parameter setting, the AUC wasestimated from 48 defect-present and 48 defect-absent images. Thecombined human observer results showed the optimum parameter settingcould be in the range 5-36 updates ([number of subsets]/iteration enumber of iterations). The CHO results showed the optimum parametersetting to be 4-5 updates. The performance of the CHO was much moresensitive to the reconstruction parameter setting than was that of thehuman observers. The rankings of the CHO detectability values did notchange with varying levels of internal noise.

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  • Journal Name: IEEE Transactions on Nuclear Science; Journal Volume: 53; Journal Issue: 3pt2; Related Information: Journal Publication Date: 06/2006

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  • Report No.: LBNL--54935
  • Grant Number: DE-AC02-05CH11231
  • Grant Number: NIHEB00121
  • Office of Scientific & Technical Information Report Number: 918548
  • Archival Resource Key: ark:/67531/metadc881735

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Reports, articles and other documents harvested from the Office of Scientific and Technical Information.

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  • July 1, 2005

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  • Sept. 22, 2016, 2:13 a.m.

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  • Dec. 13, 2016, 8:55 p.m.

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Gilland, Karen L.; Tsui, Benjamin M.W.; Qi, Yujin & Gullberg,Grant T. Comparison of Channelized Hotelling and Human Observers inDetermining Optimum OS-EM Reconstruction Parameters for MyocardialSPECT, article, July 1, 2005; Berkeley, California. (digital.library.unt.edu/ark:/67531/metadc881735/: accessed December 17, 2017), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT Libraries Government Documents Department.