Sites of Azaserine Inhibition During Photosynthesis byScenedesmus

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The success attending the use of azaserine as a specific inhibitor of one atage in the metabolic pathway leading to the synthesis of inosinic acid in pigeon liver prompted us to use this antibiotic in a similar attack on purine synthesis in Scenedesmus. However, investigation of the products produced during photosynthesis by suspensions of these algae in the presence of azaserine showed that a more widespread interference with metabolism had occurred. The purpose of this communication is to describe the nature of these effects and to attempt to assess their importance in a general picture of the metabolic effects of ... continued below

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Barker, S. Alan; Bassham, James A.; Calvin, M. & Quarck, Ursula C. May 8, 1956.

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Description

The success attending the use of azaserine as a specific inhibitor of one atage in the metabolic pathway leading to the synthesis of inosinic acid in pigeon liver prompted us to use this antibiotic in a similar attack on purine synthesis in Scenedesmus. However, investigation of the products produced during photosynthesis by suspensions of these algae in the presence of azaserine showed that a more widespread interference with metabolism had occurred. The purpose of this communication is to describe the nature of these effects and to attempt to assess their importance in a general picture of the metabolic effects of azaserine.

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  • Report No.: UCRL--3406
  • Grant Number: DE-AC02-05CH11231
  • DOI: 10.2172/915451 | External Link
  • Office of Scientific & Technical Information Report Number: 915451
  • Archival Resource Key: ark:/67531/metadc881483

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  • May 8, 1956

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  • Sept. 22, 2016, 2:13 a.m.

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  • Nov. 3, 2016, 8 p.m.

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Barker, S. Alan; Bassham, James A.; Calvin, M. & Quarck, Ursula C. Sites of Azaserine Inhibition During Photosynthesis byScenedesmus, report, May 8, 1956; Berkeley, California. (digital.library.unt.edu/ark:/67531/metadc881483/: accessed August 18, 2017), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT Libraries Government Documents Department.