In vivo cellular visualization of the human retina using optical coherence tomography and adaptive optics Page: 3 of 11
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OCT sees the human retina sharply
with adaptive optics
In vivo cellular visualization of the
human retina at micrometer-scale
resolution is possible by enhancing
tomography with adaptive optics,
which compensate for the eye's
Scot S. Olivier, Steven M. Jones,
Diana C. Chen, Robert J. Zawadzki,
Stacey S. Choi, Sophie P. Laut, and
John S. Werner
SCOT S. OLIVIER, STEVEN M. JONES, AND
DIANA C. CHEN are at Lawrence
Livermore National Laboratory, 7000
East Avenue, L-210, Livermore,
California 94550; e-mail:
firstname.lastname@example.org. ROBERT J.
ZAWADSKI, STACEY S. CHOI, SOPHIE P.
LAUT, AND JOHN S. WERNER are at the
Department of Ophthalmology and
Vision Science, UC Davis, 4860 Y
Street, Suite 2400, Sacramento, CA
Optical-coherence tomography (OCT)
recently has gained widespread
popularity among ophthalmologists for
use in the clinical diagnosis and
monitoring of human retinal disease.
The key to this success is the
ability of OCT to make noninvasive,
in vivo measurements of the thickness
of specific retinal layers--such as
the nerve-fiber layer, which thins in
patients with glaucoma. Current
commercial OCT instruments use a
"time-domain" approach in which
coherent interference between light
from the retina and a uniform
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Olivier, S S; Jones, S M; Chen, D C; Zawadzki, R J; Choi, S S; Laut, S P et al. In vivo cellular visualization of the human retina using optical coherence tomography and adaptive optics, article, January 5, 2006; Livermore, California. (digital.library.unt.edu/ark:/67531/metadc878907/m1/3/: accessed December 11, 2018), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT Libraries Government Documents Department.