Final Report on Grant DE-FG03-02ER63470

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Description

The goal of this project is to provide critical information to characterize the qualitative and quantitative similarities and difference in repair characteristics between clustered damage sites formed by ionizing radiation and singly damaged sites produced by endogenous processes. The premise is that base pairing and base stacking interactions are qualitatively and quantitatively different for singly and multiply damaged DNA sites. State-of-the-art computational chemistry model were used to characterize the structure, energetics, and spectroscopy of singly and multiply damaged (clustered) DNA sites.

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Miller, John H. November 20, 2006.

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Description

The goal of this project is to provide critical information to characterize the qualitative and quantitative similarities and difference in repair characteristics between clustered damage sites formed by ionizing radiation and singly damaged sites produced by endogenous processes. The premise is that base pairing and base stacking interactions are qualitatively and quantitatively different for singly and multiply damaged DNA sites. State-of-the-art computational chemistry model were used to characterize the structure, energetics, and spectroscopy of singly and multiply damaged (clustered) DNA sites.

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31 kB

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  • Report No.: DOE/ER/63470-1
  • Grant Number: FG03-02ER63470
  • DOI: 10.2172/895304 | External Link
  • Office of Scientific & Technical Information Report Number: 895304
  • Archival Resource Key: ark:/67531/metadc878735

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  • November 20, 2006

Added to The UNT Digital Library

  • Sept. 22, 2016, 2:13 a.m.

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  • Nov. 4, 2016, 3:33 p.m.

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Miller, John H. Final Report on Grant DE-FG03-02ER63470, report, November 20, 2006; United States. (digital.library.unt.edu/ark:/67531/metadc878735/: accessed August 17, 2017), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT Libraries Government Documents Department.