Laser Surface Engineering for Improved Biocompatibility of Orthopedic Biomaterials

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Poster presentation for the 2012 University Scholars Day at the University of North Texas discussing research on laser surface engineering for improved biocompatibility of orthopedic biomaterials.

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1 p.

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Dahotre, Sanket; Paital, Sameer & Banerjee, Rajarshi April 19, 2012.

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This poster is part of the collection entitled: UNT Scholarly Works and was provided by UNT Honors College to Digital Library, a digital repository hosted by the UNT Libraries. It has been viewed 775 times , with 35 in the last month . More information about this poster can be viewed below.

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  • Main Title: Laser Surface Engineering for Improved Biocompatibility of Orthopedic Biomaterials
  • Series Title: University Scholars Day

Description

Poster presentation for the 2012 University Scholars Day at the University of North Texas discussing research on laser surface engineering for improved biocompatibility of orthopedic biomaterials.

Physical Description

1 p.

Notes

Abstract: Even now, 90 percent of humans above the age of 40 show signs of bone degeneration as a result of society taking a turn towards more active lifestyles. This has led to a dramatic increase in the number of hip replacement surgeries. Implants today top out at around 15 years if the recipient follows a strict lifestyle protocol. As a younger demographic is now requiring prosthetic implantation surgery, it has become necessary for the implants to last longer while allowing recipients to carry on their lifestyles. These lifestyles can be hampered by flaws in current implant materials today such as low bio compatibility and varying material strength which can lead to effects such as inability to walk and insomnia caused by unbearable pain. In order to address such issues, it is becoming important to find orthopedic implant materials that do not have the previously discussed flaws. Titanium is a material that is widely being studied for strength similar to bone. However, titanium lacks in bio chemical compatibility as an orthopedic bio material. This is due to cells not recognizing the foreign metal implant due to a lack of surface chemistry and texture. In order to address this issue, the authors are proposing synthesis of a textured calcium phosphate (major constituent of human bone) based coating on the implant surface, which is likely to address both issues. Cells that surround the implant will recognize the implant as a piece of bone (due to calcium phosphate based coated surface chemistry) and try to attach (due to textured coating). Unfortunately, as the authors cannot attach to a smooth wall, cells cannot attach to the smooth surface of an implant even though the surface chemistry is adjusted to the bone chemistry via calcium phosphate coating. They require a microscale level of surface texture to adhere onto. To accomplish this, the authors used an advanced and innovative high power laser interference technique to simultaneously fuse the coating precursor to the bio material and create texture along its surface. Post surface modifications testing of the implant material for levels of cell growth compared to an untreated sample employing in-vitro culture of mouse MC3TC-E1 osteoblast cells indicated that the sample's cell coverage was much more complete than the untreated sample. Further the laser textured coatings showed improved cell adhesion via anchoring of the lamellipodia to the textured grooves and well developed network of focal adhesion contacts. Because the cells are able to grow and proliferate around the implant with much more success, patient mobility will be improved, longevity of the implant will be enhanced, and cost related to after surgery treatment and maintenance would be decreased. Additionally, amenability of laser interference textured coating technique to integration with the computer based precision and rapid prototype manufacturing holds tremendous promise for an economical manufacturing of implant parts. Thus the current research holds a tremendous promise for production of improved hard tissue implants at affordable cost to a large base patients around the globe in industrialized and under developed countries.

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  • Ninth Annual University Scholars Day, 2012, Denton, Texas, United States

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UNT Scholarly Works

Materials from the UNT community's research, creative, and scholarly activities and UNT's Open Access Repository. Access to some items in this collection may be restricted.

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Creation Date

  • April 19, 2012

Added to The UNT Digital Library

  • July 2, 2012, 5:36 p.m.

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  • Nov. 21, 2017, 8:11 p.m.

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Yesterday: 1
Past 30 days: 35
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Dahotre, Sanket; Paital, Sameer & Banerjee, Rajarshi. Laser Surface Engineering for Improved Biocompatibility of Orthopedic Biomaterials, poster, April 19, 2012; (digital.library.unt.edu/ark:/67531/metadc86824/: accessed January 19, 2018), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT Honors College.