Acetylcholine-Containing Neuroepithelial Cells in Fish Gills Support the Cholinergic Hypothesis of O2 Chemoreception Metadata

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Title

  • Main Title Acetylcholine-Containing Neuroepithelial Cells in Fish Gills Support the Cholinergic Hypothesis of O2 Chemoreception
  • Series Title University Scholars Day

Creator

  • Author: Wanner, Clinton
    Creator Type: Personal
    Creator Info: University of North Texas
  • Contributor: Burleson, Mark L.
    Creator Type: Personal
    Creator Info: University of North Texas; Faculty Mentor; burleson@unt.edu

Contributor

  • Sponsor: University of North Texas. Honors College.
    Contributor Type: Organization

Publisher

  • Name: University of North Texas. Honors College.
    Place of Publication: [Denton, Texas]

Date

  • Creation: 2011-04-14
  • Embargoed Until: 2013-04-14

Language

  • English

Description

  • Content Description: This paper discusses research on how acetylcholine-containing neuroepithelial cells in fish gills support the cholinergic hypothesis of O2 chemoreception.
  • Physical Description: 15 p.

Subject

  • Keyword: O2 chemoreceptors
  • Keyword: neurotransmitters
  • Keyword: fish gills

Source

  • Journal: The Eagle Feather, 2011, Denton: University of North Texas. Honors College

Citation

  • Publication Title: The Eagle Feather
  • Issue: 2011
  • Volume: 8
  • Peer Reviewed: True

Relation

  • Is Version Of: Acetylcholine-Containing Neuroepithelial Cells in Fish Gills Support the Cholinergic Hypothesis of O2 Chemoreception [Presentation], ark:/67531/metadc93292

Collection

  • Name: UNT Scholarly Works
    Code: UNTSW

Institution

  • Name: UNT Honors College
    Code: UNTHON

Rights

  • Rights Access: public

Resource Type

  • Paper

Format

  • Text

Identifier

  • DOI: 10.12794/tef.2011.248
  • Archival Resource Key: ark:/67531/metadc86190

Degree

  • Academic Department: Biological Sciences

Note

  • Embargo Note: This item has a 2 year embargo period. For more information on this item or to inquire about obtaining a copy, please contact the authors directly.
  • Display Note: Abstract: The neurochemical link between O2 chemoreceptors and afferent nerves that carry information about O2 levels to cardio-ventilatory centers in the brain has yet to be determined. This study examines the roles of two candidate neurotransmitters thought to be involved in O2 chemoreception, using channel catfish, Ictalurus punctatus. Fish gills are the evolutionary progenitors of arterial arches (aortic and carotid) of mammals where O2 chemoreceptors are located. Neuroepithelial cells (NECs) containing serotonin (5-HT) and acetylcholine (Ach) were confirmed in the first gill arch using immunohistochemistry and laser confocal microscopy. 5-HT-containing NECs were aggregated around the efferent branchial artery, near tips of filaments and lamellae, ACh-containing NECs at the distal tips of filaments. Preliminary co-localization experiments indicate separate 5-HT and Ach-containing cells. This is the first demonstration of ACh-containing NECs and results of this study support pharmacological studies suggesting that ACh is the primary neurochemical involved in O2 chemoreception in vertebrates.
  • Display Note: Eighth Annual University Scholars Day, 2011, Denton, Texas, United States.