The UNT Honors College is dedicated to enriching the undergraduate academic experience for talented, motivated, and well-prepared students. The college offers its members many benefits, including challenging classes, training in research methods and skills, eligibility to live in Rawlins Hall or Honors Hall, and a supportive social and academic environment.
Poster for the 2010 University Scholars Day at the University of North Texas discussing research on primary cilia in the oligodendrocyte lineage.
Physical Description
1 p.
Notes
Abstract: Primary cilia are hairlike, nonmotile organelles almost entirely universal in vertebrate cells. Primary cilia are required for neurogenesis and the expansion of certain neural progenitor populations in the brain. Cilia have not been identified in oligodendrocytes, the glial cells responsible for myelination of axons in the central nervous system. Although oligodendrocytes may be an exception to ciliated vertebrate cells, the presence of oligodendrocytes depends upon sonic hedgehog signaling (Shh) which does depend upon the presence of primary cilia. This signifies that primary cilia may in fact be present somewhere in the oligodendrocyte lineage. Research in our lab is showing that during development, oligodendrocyte progenitors frequently have cilia, but lose them early in differentiation into mature oligodendrocytes. Research has shown that a small number of adult oligodendrocyte progenitors have cilia. My research proposes to expand the study of ciliation among the oligodendrocyte lineage in the developing and adult brain.
This poster is part of the following collection of related materials.
UNT Undergraduate Student Works
This collection presents scholarly and artistic content created by undergraduate students. All materials have been previously accepted by a professional organization or approved by a faculty mentor. Most classroom assignments are not eligible for inclusion. The collection includes, but is not limited to Honors College theses, thesis supplemental files, professional presentations, articles, and posters. Some items in this collection are restricted to use by the UNT community.
