Primary Cilia in the Oligodendrocyte Lineage: New Insights

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Poster for the 2010 University Scholars Day at the University of North Texas discussing research on primary cilia in the oligodendrocyte lineage.

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1 p.

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Valliere, Sarah & Fuchs, Jannon L. April 15, 2010.

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This poster is part of the collection entitled: UNT Scholarly Works and was provided by UNT Honors College to Digital Library, a digital repository hosted by the UNT Libraries. It has been viewed 949 times , with 152 in the last month . More information about this poster can be viewed below.

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Description

Poster for the 2010 University Scholars Day at the University of North Texas discussing research on primary cilia in the oligodendrocyte lineage.

Physical Description

1 p.

Notes

Abstract: Primary cilia are hairlike, nonmotile organelles almost entirely universal in vertebrate cells. Primary cilia are required for neurogenesis and the expansion of certain neural progenitor populations in the brain. Cilia have not been identified in oligodendrocytes, the glial cells responsible for myelination of axons in the central nervous system. Although oligodendrocytes may be an exception to ciliated vertebrate cells, the presence of oligodendrocytes depends upon sonic hedgehog signaling (Shh) which does depend upon the presence of primary cilia. This signifies that primary cilia may in fact be present somewhere in the oligodendrocyte lineage. Research in our lab is showing that during development, oligodendrocyte progenitors frequently have cilia, but lose them early in differentiation into mature oligodendrocytes. Research has shown that a small number of adult oligodendrocyte progenitors have cilia. My research proposes to expand the study of ciliation among the oligodendrocyte lineage in the developing and adult brain.

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  • Seventh Annual University Scholars Day, 2010, Denton, Texas, United States

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UNT Scholarly Works

Materials from the UNT community's research, creative, and scholarly activities and UNT's Open Access Repository. Access to some items in this collection may be restricted.

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Creation Date

  • April 15, 2010

Added to The UNT Digital Library

  • June 8, 2012, 10:10 a.m.

Description Last Updated

  • Nov. 21, 2017, 9:07 p.m.

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Past 30 days: 152
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Valliere, Sarah & Fuchs, Jannon L. Primary Cilia in the Oligodendrocyte Lineage: New Insights, poster, April 15, 2010; (digital.library.unt.edu/ark:/67531/metadc86145/: accessed December 12, 2017), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT Honors College.