A High Resolution Monolithic Crystal, DOI, MR Compatible, PET Detector Page: 4 of 8
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Finally we did a simulation study using measured intrinsic detector response functions to investigate image-
based figures of merit for small animal PET systems. We simulated two systems using conventional detector
readout and one system using SES readout. For the first conventional detector system we used an 8 mm thick
crystal detector (representing high spatial resolution). For the second conventional detector system we used a
15 mm thick crystal detector (representing high sensitivity). For the SES detector system we use a 15 mm
thick crystal detector (representing both high detection efficiency and high spatial resolution). The results of
the study were that the SES detector provided the best overall performance. It provided similar quantitative
imaging performance as the 8mm thick conventional readout detector and better quantitative imaging
performance than the 15 mm thick conventional detector system, as quantitative imaging performance is
largely driven by spatial resolution. It also provided similar detection performance as the 15 mm thick
conventional readout detector and better detection performance than the 8 mm thick conventional detector, as
detection performance is driven by sensitivity.
SES cMiCE PET detector electronics (data acquisition electronics, specific aim 2).
We initially started out using
SensL SiPM devices and their.;,
front end electronics;
however, the devices had V '
problems with cross-talk
between the SiPM macro-
cells due to routing of the
power and output signal lines.
We also did some initial
investigation with a Zecotek
2-D SiPM array; however,
that device also had less than Figure 2. Pictures of 2D SiPM
optimum characteristics (i.e., Figure 1. Photograph of an 8x8 SiPM array next to a 32.55 mm by arrays from Philips with and
>10 gain variability between 32.55 mm by 15 mm LYSO crystal. without flex circuit cable
SiPM macro-cells). During assembly.
the progress of this grant we
obtained funding to work with Philips Medical Systems
to further develop the SES detector concept with the - -
goal of building a complete scanner with SES detectors.
Through our association with Philips we got access to 2-
D SiPM arrays, as pictured in Figure 1, and began
working with those devices. After we received the 2D-
SiPM arrays we worked with a local company to develop -
a flex cable connector that allows us to route the SiPM
signal to our electronics boards when using the SES
design. An SiPM array with flex cables attached is
pictured in Figure 2. In addition to the 2-D SiPM arrays Figure 3. Photograph of UWdata acquisition electronics board to
we also obtained frontend detector electronics and a support the SES cMiCE detector design.
data acquisition system to collect signals from the 2D
arrays. While the data acquisition system is rather bulky,
it has much higher bandwidth than the VME acquisition
system that we also have in our laboratory. Therefore
we used the SiPM arrays and data acquisition system
from Philips Medical Systems for the initial evaluation of /
our SES detector design.
In addition to the electronics and data acquisition system
described above we also continued to develop more)
compact data acquisition boards customized to the
needs of our detector design. A photograph of the board Figure 4. Picture of temperature
we developed is shown in Figure 3. The board has a controlled light tight box, data
large FPGA on it and supports data acquisition of 65 acquisition computer, and detector
signal channels. It can digitize up to 64 channels at 65M right: SES detector assembly with tile s". mm
samples per second and one channel at 300M samples mounted on entrance surface.
per second. It communicates to an acquisition computer
via FireWire. Using the FireWire protocol allows up to 63 of these boards to be daisy chained together with
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Miyaoka, Robert S. A High Resolution Monolithic Crystal, DOI, MR Compatible, PET Detector, report, March 6, 2012; United States. (https://digital.library.unt.edu/ark:/67531/metadc837330/m1/4/: accessed April 23, 2024), University of North Texas Libraries, UNT Digital Library, https://digital.library.unt.edu; crediting UNT Libraries Government Documents Department.