The Genome of the Western Clawed Frog Xenopus tropicalis Page: 82 of 86
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gastrin neuropeptides, encoded by a single exon. However, the genes encoding
cholecystokinin (scaffold_1166), xenoxin (scaffold_521) and TRH (scaffold_353) are
located on separate scaffolds, and in syntenic regions compared to mammalian genomes.
Thus the structure of the antimicrobial peptide locus reflects the combinatorial
rearrangements of exons that occurred during evolution. It is tempting to speculate that
splicing events may produce different mRNA encoding different preproproteins; these
might encode a variety of peptides that mediate aspects of innate immunity.
Table S17: antimicrobial genes
CDNA (Xentr4)
Pglaxentr scaffold_811:21284-21414,24320-24350,25963-26022,27347-27509
Levitidexentr scaffold 811:234823-234876,238354-238517,242742-242789,244266-244346,249729
magaininxentr scaffold_811:272044-272092,275080-275231,276929-276991,278721-278779
caeruleinxentr scaffold 811:300765-300847,302701-302849,304911-304964,306529-306698
caerulein2 xentr scaffold 811:343808-343954,345109-345194,347389-347537,348657-348694
prepropgqxentr scaffold_811:47814-47950,50296-50387,52003-52071,53604-53761,54914-54957
prepropgq2_xentrscaffold_811:68508-68616,71069-71153,71843-71911,75139-75296,81538-81572
cholecystokinin scaffold_1166:19699-35312
Xenoxin scaffold 521:624513-626954
TRH scaffold 353:194552-202299
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Hellsten, Uffe; Harland, Richard M.; Gilchrist, Michael J.; Hendrix, David; Jurka, Jerzy; Kapitonov, Vladimir et al. The Genome of the Western Clawed Frog Xenopus tropicalis, article, October 1, 2009; Berkeley, California. (https://digital.library.unt.edu/ark:/67531/metadc831346/m1/82/: accessed April 17, 2024), University of North Texas Libraries, UNT Digital Library, https://digital.library.unt.edu; crediting UNT Libraries Government Documents Department.