Apical polarity in three-dimensional culture systems: where to now?

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Delineation of the mechanisms that establish and maintain the polarity of epithelial tissues is essential to understanding morphogenesis, tissue specificity and cancer. Three-dimensional culture assays provide a useful platform for dissecting these processes but, as discussed in a recent study in BMC Biology on the culture of mammary gland epithelial cells, multiple parameters that influence the model must be taken into account.

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Inman, J. L. & Bissell, Mina January 21, 2010.

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Delineation of the mechanisms that establish and maintain the polarity of epithelial tissues is essential to understanding morphogenesis, tissue specificity and cancer. Three-dimensional culture assays provide a useful platform for dissecting these processes but, as discussed in a recent study in BMC Biology on the culture of mammary gland epithelial cells, multiple parameters that influence the model must be taken into account.

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  • Journal Name: Journal of Biology; Journal Volume: 9; Journal Issue: 1; Related Information: Journal Publication Date: 1/21/2010

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  • Report No.: LBNL-4096E
  • Grant Number: DE-AC02-05CH11231
  • Grant Number: R01CA064786, R01CA057621, U54CA126552, U54CA112970, U54CA143836
  • DOI: 10.1186/jbiol213 | External Link
  • Office of Scientific & Technical Information Report Number: 1000961
  • Archival Resource Key: ark:/67531/metadc830118

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Office of Scientific & Technical Information Technical Reports

Reports, articles and other documents harvested from the Office of Scientific and Technical Information.

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  • January 21, 2010

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  • May 19, 2016, 3:16 p.m.

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  • June 15, 2016, 10:02 p.m.

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Inman, J. L. & Bissell, Mina. Apical polarity in three-dimensional culture systems: where to now?, article, January 21, 2010; Berkeley, California. (digital.library.unt.edu/ark:/67531/metadc830118/: accessed October 23, 2018), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT Libraries Government Documents Department.