Annotation of the Clostridium Acetobutylicum Genome

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Description

The genome sequence of the solvent producing bacterium Clostridium acetobutylicum ATCC824, has been determined by the shotgun approach. The genome consists of a 3.94 Mb chromosome and a 192 kb megaplasmid that contains the majority of genes responsible for solvent production. Comparison of C. acetobutylicum to Bacillus subtilis reveals significant local conservation of gene order, which has not been seen in comparisons of other genomes with similar, or, in some cases, closer, phylogenetic proximity. This conservation allows the prediction of many previously undetected operons in both bacteria.

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Daly, M. J. June 9, 2004.

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Description

The genome sequence of the solvent producing bacterium Clostridium acetobutylicum ATCC824, has been determined by the shotgun approach. The genome consists of a 3.94 Mb chromosome and a 192 kb megaplasmid that contains the majority of genes responsible for solvent production. Comparison of C. acetobutylicum to Bacillus subtilis reveals significant local conservation of gene order, which has not been seen in comparisons of other genomes with similar, or, in some cases, closer, phylogenetic proximity. This conservation allows the prediction of many previously undetected operons in both bacteria.

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OSTI as DE00830021

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  • Other Information: PBD: 9 Jun 2004

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  • Grant Number: FG02-00ER62924
  • DOI: 10.2172/830021 | External Link
  • Office of Scientific & Technical Information Report Number: 830021
  • Archival Resource Key: ark:/67531/metadc787145

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  • June 9, 2004

Added to The UNT Digital Library

  • Dec. 3, 2015, 9:30 a.m.

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  • Aug. 4, 2016, 7:32 p.m.

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Daly, M. J. Annotation of the Clostridium Acetobutylicum Genome, report, June 9, 2004; United States. (digital.library.unt.edu/ark:/67531/metadc787145/: accessed August 21, 2017), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT Libraries Government Documents Department.