Engineered Antibodies for Monitoring of Polynuclear Aromatic Hydrocarbons Page: 4 of 4
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ANNUAL TECHNICAL PROGRESS REPORT, AWARD No DE-FG07-96ER62316 4
Aug. 1998 - Aug. 1999
Ridge National Laboratory to identify a sensor system and demonstration project to move our
work closer to deployment.
PUBLICATIONS AND ABSTRACTS (LAST 12 MONTHS)
1998 Karu, A. E., Q. X. Li and V. Roberts. Engineered antibodies for monitoring of polynuclear aromatic
hydrocarbons. (Poster presented at Dept. of Energy Environmental Science Management Program
Workshop, Chicago, IL (July 27-30). http://www.doe.gov/em52/1998posters/id54546.pdf
1998 Liu, M., G. A. Rechnitz, K. Li and Q. X. Li. Capacitive immunosensing of polycyclic aromatic
hydrocarbon and protein conjugates. Anal. Lett. 31:2025-2038
1999 Li, K., R. Chen, B. Zhao, M. Liu, A. E. Karu, V. A. Roberts and Q. X. Li. Monoclonal antibody-based
enzyme-linked immunosorbent assays for part-per-billion determination of polycyclic aromatic
hydrocarbons: Effects of haptens and formats on sensitivity and specificity. Anal. Chem. 71:302-309
1999 Guo, F., Q. X. Li and J. P. Alcantara-Licudine. A simple Na4EDTA-assisted sub/supercritical fluid
extraction procedure for quantitative recovery of polar analytes in soil. Anal. Chem. 71:1309-1315
1999 Liu, M., Q. X. Li and G. A. Rechnitz. Flow injection immunosensing of polycyclic aromatic hydrocarbon
with a quartz crystal microbalance. Analyt. Chim. Acta 387: 29-38.
1999 Liu, M., Q. X. Li and G. A. Rechnitz. Gold electrode modification with thiolated hapten for the design of
amperometric and piezoelectric immunosensors. Electrochem. Anal. (in Press).
1999 Pellequer, J.-L.; Zhao, B.; Kao, H.-J.; Karu, A. E.; Roberts, V. A.; Cation-pi interactions in antibody
binding of polynuclear aromatic hydrocarbons (Abstract No. 36750); Symposium on First
Accomplishments of the Enviironmental Management Science Program, ACS Div. of Nuclear Chemistry
and Technology, 218th National Meeting, American Chemical Society, New Orleans, LA, Aug 22-26
1999 Li, Q. X., K. Li, S. Thomas and H. Li. Application of immunochemical methods for the analysis of
polynuclear aromatic hydrocarbons in the environment (Abstract No. NUCL0047). Symposium on First
Accomplishments of the Environmental Management Science Program, 218th National Meeting, American
Chemical Society, New Orleans, LA, Aug 22-26
1999 Thomas, S. and Q. X. Li. Immunoaffinity chromatography for the analysis of polycyclic
aromatic hydrocarbons in coral. Environ. Sci. Technol. (submitted Sept. 99):
PERSONNEL INVOLVED:
University of Calif., Berkeley:
Alexander E. Karu (PI)
Christopher W. Bell, Ph.D. (postdoctoral) Oct. 96 - April 97
Bitao Zhao (M.S. in Medicinal Chemistry) Feb. 97 - June 1998
Hui-I Kao (Accepted into Ph.D. program in biochemistry, Univ. of Rochester,
Sept. 1999.) May 1998 - June 1999
The Scripps research Institute:
Victoria A. Roberts (Associate Professor; Co-PI)
Jean-Luc Pellequer (Post-doctoral Research Associate)
University of Hawaii at Manoa:
Qing Xiao Li, (Associate Professor; Co-PI)
Rongliang Chen, (chemist, supported in part)
F. Guo (postdoctoral fellow, supported in part)
H.Li (graduate student, supported in part)
Kai Li (postdoctoral fellow, supported in full)
M. Liu (graduate student, supported in part)
S. Thomas (graduate student, supported in full)
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Karu, Alexander E.; Roberts, Victoria & Li, Qingxiao. Engineered Antibodies for Monitoring of Polynuclear Aromatic Hydrocarbons, report, June 1, 1999; United States. (https://digital.library.unt.edu/ark:/67531/metadc786125/m1/4/: accessed April 24, 2024), University of North Texas Libraries, UNT Digital Library, https://digital.library.unt.edu; crediting UNT Libraries Government Documents Department.