Monte Carol-Based Dosimetry of Beta-Emitters for Intravascular Brachytherapy

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Monte Carlo simulations for radiation dosimetry and the experimental verifications of the simulations have been developed for the treatment geometry of intravascular brachytherapy, a form of radionuclide therapy for occluded coronary disease (restenosis). Monte Carlo code, MCNP4C, has been used to calculate the radiation dose from the encapsulated array of B-emitting seeds (Sr/Y-source train). Solid water phantoms have been fabricated to measure the dose on the radiochromic films that were exposed to the beta source train for both linear and curved coronary vessel geometries. While the dose difference for the 5-degree curved vessel at the prescription point of f+2.0 mm ... continued below

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Choi, C.K. June 25, 2002.

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Monte Carlo simulations for radiation dosimetry and the experimental verifications of the simulations have been developed for the treatment geometry of intravascular brachytherapy, a form of radionuclide therapy for occluded coronary disease (restenosis). Monte Carlo code, MCNP4C, has been used to calculate the radiation dose from the encapsulated array of B-emitting seeds (Sr/Y-source train). Solid water phantoms have been fabricated to measure the dose on the radiochromic films that were exposed to the beta source train for both linear and curved coronary vessel geometries. While the dose difference for the 5-degree curved vessel at the prescription point of f+2.0 mm is within the 10% guideline set by the AAPM, however, the difference increased dramatically to 16.85% for the 10-degree case which requires additional adjustment for the acceptable dosimetry planning. The experimental dose measurements agree well with the simulation results

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OSTI as DE00798524

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  • Other Information: PBD: 25 Jun 2002

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  • Report No.: DOE/NEER/PURDUE-C03-02
  • Grant Number: FG07-99ID13782
  • DOI: 10.2172/798524 | External Link
  • Office of Scientific & Technical Information Report Number: 798524
  • Archival Resource Key: ark:/67531/metadc738508

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  • June 25, 2002

Added to The UNT Digital Library

  • Oct. 19, 2015, 7:39 p.m.

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  • Jan. 3, 2017, 12:55 p.m.

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Choi, C.K. Monte Carol-Based Dosimetry of Beta-Emitters for Intravascular Brachytherapy, report, June 25, 2002; United States. (digital.library.unt.edu/ark:/67531/metadc738508/: accessed November 21, 2017), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT Libraries Government Documents Department.