THE USE OF POSITRON EMISSION TOMOGRAPHY IN IDENTIFYING AND QUANTIFYING RECEPTORS INVOLVED IN SCHIZOPHRENIA.

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Schizophrenia is a devasting mental disorder that is the focus of a great deal of research. Some symptoms of the disease, such as auditory hallucinations and delusions, can be ameliorated with drug treatment, whereas other symptoms, such as social withdrawal and cognitive decline, remain uncontrolled. It is possible that these latter symptoms that are often termed ''negative symptoms'' are the result of anatomical and neurochemical abnormalities, whereas those symptoms of the disease such as auditory hallucinations that are termed ''positive symptoms'' may be a result of only neurochemical disorders. The drugs used to treat schizophrenia are designated neuroleptics. The term ... continued below

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14 pages

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Volkow, N. D. & Wolf, A. P. January 1991.

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Description

Schizophrenia is a devasting mental disorder that is the focus of a great deal of research. Some symptoms of the disease, such as auditory hallucinations and delusions, can be ameliorated with drug treatment, whereas other symptoms, such as social withdrawal and cognitive decline, remain uncontrolled. It is possible that these latter symptoms that are often termed ''negative symptoms'' are the result of anatomical and neurochemical abnormalities, whereas those symptoms of the disease such as auditory hallucinations that are termed ''positive symptoms'' may be a result of only neurochemical disorders. The drugs used to treat schizophrenia are designated neuroleptics. The term neuroleptic was chosen to emphasize the similarity of pharmacological profiles of drugs with entirely different chemical structures. Especially prominent features of the effects of neuroleptics include the following: a state of affective indifference; a decrease in locomotor activity; a decrease in excitation, agitation, and aggressiveness; and an antipsychotic action in patients with acute as well as chronic psychoses.

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14 pages

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  • Other Information: BOOK TITLE:POSITRON EMISSION TOMOGRAPHY IN SCHIZOPHRENIA RESEAECH, EDITED BY N.D.VOLKOW, A.P.WOLF, SERIES:PROGRESS IN PSYCHIATRY, NO.33, SERIES EDITOR D.SPIEGEL, AMERICAN PSYCHIATRIC PRESS, INC., WASHINGTON,DC

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  • Report No.: BNL--69212
  • Grant Number: AC02-98CH10886
  • Office of Scientific & Technical Information Report Number: 798546
  • Archival Resource Key: ark:/67531/metadc733823

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Office of Scientific & Technical Information Technical Reports

Reports, articles and other documents harvested from the Office of Scientific and Technical Information.

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  • January 1991

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  • Oct. 19, 2015, 7:39 p.m.

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  • Nov. 9, 2015, 9:10 p.m.

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Volkow, N. D. & Wolf, A. P. THE USE OF POSITRON EMISSION TOMOGRAPHY IN IDENTIFYING AND QUANTIFYING RECEPTORS INVOLVED IN SCHIZOPHRENIA., book, January 1991; Upton, New York. (digital.library.unt.edu/ark:/67531/metadc733823/: accessed December 14, 2017), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT Libraries Government Documents Department.