Monte Carlo Simulations of Arterial Imaging with Optical Coherence Tomography

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The laser-tissue interaction code LATIS [London et al., Appl. Optics 36, 9068 ( 1998)] is used to analyze photon scattering histories representative of optical coherence tomography (OCT) experiment performed at Lawrence Livermore National Laboratory. Monte Carlo photonics with Henyey-Greenstein anisotropic scattering is implemented and used to simulate signal discrimination of intravascular structure. An analytic model is developed and used to obtain a scaling law relation for optimization of the OCT signal and to validate Monte Carlo photonics. The appropriateness of the Henyey-Greenstein phase function is studied by direct comparison with more detailed Mie scattering theory using an ensemble of spherical ... continued below

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6,100 Kilobytes pages

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Amendt, P.; Estabrook, K.; Everett, M.; London, R.A.; Maitland, D.; Zimmerman, G. et al. February 1, 2000.

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The laser-tissue interaction code LATIS [London et al., Appl. Optics 36, 9068 ( 1998)] is used to analyze photon scattering histories representative of optical coherence tomography (OCT) experiment performed at Lawrence Livermore National Laboratory. Monte Carlo photonics with Henyey-Greenstein anisotropic scattering is implemented and used to simulate signal discrimination of intravascular structure. An analytic model is developed and used to obtain a scaling law relation for optimization of the OCT signal and to validate Monte Carlo photonics. The appropriateness of the Henyey-Greenstein phase function is studied by direct comparison with more detailed Mie scattering theory using an ensemble of spherical dielectric scatterers. Modest differences are found between the two prescriptions for describing photon angular scattering in tissue. In particular, the Mie scattering phase functions provide less overall reflectance signal but more signal contrast compared to the Henyey-Greenstein formulation.

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6,100 Kilobytes pages

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  • Conference on Gastrointestinal Surgery, San Jose, CA (US), 01/22/2000

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  • Report No.: UCRL-JC-135024
  • Grant Number: W-7405-Eng-48
  • Office of Scientific & Technical Information Report Number: 790961
  • Archival Resource Key: ark:/67531/metadc719446

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  • February 1, 2000

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  • Sept. 29, 2015, 5:31 a.m.

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  • May 6, 2016, 2:49 p.m.

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Amendt, P.; Estabrook, K.; Everett, M.; London, R.A.; Maitland, D.; Zimmerman, G. et al. Monte Carlo Simulations of Arterial Imaging with Optical Coherence Tomography, article, February 1, 2000; California. (digital.library.unt.edu/ark:/67531/metadc719446/: accessed August 18, 2017), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT Libraries Government Documents Department.