A compact, discrete CsI(Tl) scintillator/Si photodiode gamma camera for breast cancer imaging

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Recent clinical evaluations of scintimammography (radionuclide breast imaging) are promising and suggest that this modality may prove a valuable complement to X-ray mammography and traditional breast cancer detection and diagnosis techniques. Scintimammography, however, typically has difficulty revealing tumors that are less than 1 cm in diameter, are located in the medial part of the breast, or are located in the axillary nodes. These shortcomings may in part be due to the use of large, conventional Anger cameras not optimized for breast imaging. In this thesis I present compact single photon camera technology designed specifically for scintimammography which strives to alleviate ... continued below

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242 pages

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Gruber, Gregory J. Autumn 2000.

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Description

Recent clinical evaluations of scintimammography (radionuclide breast imaging) are promising and suggest that this modality may prove a valuable complement to X-ray mammography and traditional breast cancer detection and diagnosis techniques. Scintimammography, however, typically has difficulty revealing tumors that are less than 1 cm in diameter, are located in the medial part of the breast, or are located in the axillary nodes. These shortcomings may in part be due to the use of large, conventional Anger cameras not optimized for breast imaging. In this thesis I present compact single photon camera technology designed specifically for scintimammography which strives to alleviate some of these limitations by allowing better and closer access to sites of possible breast tumors. Specific applications are outlined. The design is modular, thus a camera of the desired size and geometry can be constructed from an array (or arrays) of individual modules and a parallel hole lead collimator for directional information. Each module consists of: (1) an array of 64 discrete, optically-isolated CsI(Tl) scintillator crystals 3 x 3 x 5 mm{sup 3} in size, (2) an array of 64 low-noise Si PIN photodiodes matched 1-to-1 to the scintillator crystals, (3) an application-specific integrated circuit (ASIC) that amplifies the 64 photodiode signals and selects the signal with the largest amplitude, and (4) connectors and hardware for interfacing the module with a motherboard, thereby allowing straightforward computer control of all individual modules within a camera.

Physical Description

242 pages

Notes

INIS; OSTI as DE00780592

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  • Other Information: TH: Thesis (Ph.D.); Submitted to the Univ. of California, Berkeley, CA (US); Univ. of California, San Francisco, CA (US)

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  • Report No.: LBNL--47620
  • Grant Number: AC03-76SF00098
  • Grant Number: DAMD17-98-1-8302
  • Office of Scientific & Technical Information Report Number: 780592
  • Archival Resource Key: ark:/67531/metadc715180

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Office of Scientific & Technical Information Technical Reports

Reports, articles and other documents harvested from the Office of Scientific and Technical Information.

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  • Autumn 2000

Added to The UNT Digital Library

  • Sept. 29, 2015, 5:31 a.m.

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  • April 5, 2016, 1:15 p.m.

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Gruber, Gregory J. A compact, discrete CsI(Tl) scintillator/Si photodiode gamma camera for breast cancer imaging, thesis or dissertation, Autumn 2000; California. (digital.library.unt.edu/ark:/67531/metadc715180/: accessed January 17, 2018), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT Libraries Government Documents Department.