Testing the validity of a receptor kinetic model via TcNGA functional imaging of liver transplant recipients. Final report

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The author had accomplished the expertise for I-125-HSA plasma volume, galactose clearance for determination of hepatic plasma flow as well as finalizing the kinetic model. They have just completed modifying the microscale Scatchard assay for greater precision of receptor measurement using only 5--10 mg of liver tissue. In addition, he determined during the past year that the most practical method and clinically reasonable measurement of liver volume was to measure the transplanted liver in vivo using Tc-NGA images in the anterior, posterior, and right lateral projections, using the method of Rollo and DeLand. Direct measurement of liver weight obtained during ... continued below

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3 p.

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Stadalnik, R. C. March 25, 1993.

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Description

The author had accomplished the expertise for I-125-HSA plasma volume, galactose clearance for determination of hepatic plasma flow as well as finalizing the kinetic model. They have just completed modifying the microscale Scatchard assay for greater precision of receptor measurement using only 5--10 mg of liver tissue. In addition, he determined during the past year that the most practical method and clinically reasonable measurement of liver volume was to measure the transplanted liver in vivo using Tc-NGA images in the anterior, posterior, and right lateral projections, using the method of Rollo and DeLand. Direct measurement of liver weight obtained during transplant operation was not reliable due to variability of fluid retention in the donor liver secondary to ischemia, preservation fluid, etc., which thereby did not reflect an accurate liver weight which is needed in the kinetic analysis comparison, i.e., V{sub h} (hepatic plasma volume).

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3 p.

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INIS; OSTI as DE99000075

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  • Other Information: PBD: 25 Mar 1993

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  • Other: DE99000075
  • Report No.: DOE/ER/60553--T1
  • Grant Number: FG03-87ER60553
  • DOI: 10.2172/666247 | External Link
  • Office of Scientific & Technical Information Report Number: 666247
  • Archival Resource Key: ark:/67531/metadc712118

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  • March 25, 1993

Added to The UNT Digital Library

  • Sept. 12, 2015, 6:31 a.m.

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  • Nov. 5, 2015, 6:57 p.m.

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Stadalnik, R. C. Testing the validity of a receptor kinetic model via TcNGA functional imaging of liver transplant recipients. Final report, report, March 25, 1993; United States. (digital.library.unt.edu/ark:/67531/metadc712118/: accessed October 24, 2017), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT Libraries Government Documents Department.