Radium in humans: A review of U.S. studies

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This document was originally conceived as a description of the radium studies that took place at Argonne National Laboratory. It soon became evident, however, that to document the widespread use of radium, a brief review of the application of radium in medicine and in the US dial painting industry is required. Further, because the Argonne studies were not the only such efforts, brief overviews of the other radium programs are included. Even so, much material has been omitted. The extensive references included will allow the interested reader to find additional information. The effects of internally deposited radium in humans have ... continued below

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246 pages

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Rowland, R.E. February 10, 1995.

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This report is part of the collection entitled: Office of Scientific & Technical Information Technical Reports and was provided by UNT Libraries Government Documents Department to Digital Library, a digital repository hosted by the UNT Libraries. It has been viewed 155 times , with 7 in the last month . More information about this report can be viewed below.

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Description

This document was originally conceived as a description of the radium studies that took place at Argonne National Laboratory. It soon became evident, however, that to document the widespread use of radium, a brief review of the application of radium in medicine and in the US dial painting industry is required. Further, because the Argonne studies were not the only such efforts, brief overviews of the other radium programs are included. Even so, much material has been omitted. The extensive references included will allow the interested reader to find additional information. The effects of internally deposited radium in humans have been studied in this country for more than 75 years. Some 2,400 subjects have had their body contents of radium measured, and a majority of them have been followed for most of their adult lives, to understand and quantify the effects of radium. Many more individuals acquired radium internally but were never measured. Some of this group have been located and followed until death; in these cases the cause of death is known without a body content measurement. As a consequence of the efforts made to locate, measure, and follow exposed individuals, a great deal of information about the effects of radium is available. Nevertheless, great gaps remain in the knowledge of radium toxicity. The Argonne study is the largest every undertaken of the effects on humans of an internally deposited radioelement, in which the insult has been quantitated by actual measurements of the retained radioisotope. The study has now been terminated, even though more than 1,000 subjects with measured radium burdens are still alive. This document is written as a brief summary of current knowledge accumulated in this incomplete study.

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246 pages

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  • Other Information: PBD: 10 Feb 1995

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  • Report No.: ANL/ER--3
  • Grant Number: W-31109-ENG-38
  • DOI: 10.2172/751062 | External Link
  • Office of Scientific & Technical Information Report Number: 751062
  • Archival Resource Key: ark:/67531/metadc708597

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Office of Scientific & Technical Information Technical Reports

Reports, articles and other documents harvested from the Office of Scientific and Technical Information.

Office of Scientific and Technical Information (OSTI) is the Department of Energy (DOE) office that collects, preserves, and disseminates DOE-sponsored research and development (R&D) results that are the outcomes of R&D projects or other funded activities at DOE labs and facilities nationwide and grantees at universities and other institutions.

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Creation Date

  • February 10, 1995

Added to The UNT Digital Library

  • Sept. 12, 2015, 6:31 a.m.

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  • May 23, 2016, 2:23 p.m.

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Rowland, R.E. Radium in humans: A review of U.S. studies, report, February 10, 1995; Argonne, Illinois. (digital.library.unt.edu/ark:/67531/metadc708597/: accessed December 16, 2018), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT Libraries Government Documents Department.