Structure, dynamics, and function of biomolecules

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This is the final report of a three-year, Laboratory Directed Research and Development (LDRD) project at the Los Alamos National Laboratory (LANL). The authors enhanced Los Alamos' core competency in Bioscience and Biotechnology by building on present strengths in experimental techniques, theory, high-performance computing, modeling, and simulation applied to biomolecular structure, dynamics, and function. Specifically, the authors strengthened their capabilities in neutron/x-ray scattering, x-ray crystallography, NMR, laser, and optical spectroscopies. Initially they focused on supporting the Los alamos Neutron Science Center (LANSCE) in the design and implementation of new neutron scattering instrumentation, they developed new methods for analysis of scattering ... continued below

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10 pages

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Frauenfelder, H.; Berendzen, J.R.; Garcia, A.; Gupta, G.; Olah, G. A.; Terwilliger, T. C. et al. November 1998.

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This report is part of the collection entitled: Office of Scientific & Technical Information Technical Reports and was provided by UNT Libraries Government Documents Department to Digital Library, a digital repository hosted by the UNT Libraries. It has been viewed 27 times . More information about this report can be viewed below.

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Description

This is the final report of a three-year, Laboratory Directed Research and Development (LDRD) project at the Los Alamos National Laboratory (LANL). The authors enhanced Los Alamos' core competency in Bioscience and Biotechnology by building on present strengths in experimental techniques, theory, high-performance computing, modeling, and simulation applied to biomolecular structure, dynamics, and function. Specifically, the authors strengthened their capabilities in neutron/x-ray scattering, x-ray crystallography, NMR, laser, and optical spectroscopies. Initially they focused on supporting the Los alamos Neutron Science Center (LANSCE) in the design and implementation of new neutron scattering instrumentation, they developed new methods for analysis of scattering data, and they developed new projects to study the structures of biomolecular complexes. The authors have also worked to strengthen interactions between theory and experiment, and between the biological and physical sciences. They sponsored regular meetings of members from all interested LANL technical divisions, and supported two lecture series: ''Biology for Physicists'' and ''Issues in Modern Biology''. They also supported the formation of interdisciplinary/inter-divisional teams to develop projects in science-based bioremediation and an integrated structural biology resource. Finally, they successfully worked with a multidisciplinary team to put forward the Laboratory's Genome and Beyond tactical goal.

Physical Description

10 pages

Notes

INIS; OSTI as DE00674922

Source

  • Other Information: Supercedes report DE99000817; PBD: [1998]

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  • Other: DE99000817
  • Report No.: LA-UR--98-2093
  • Grant Number: W-7405-ENG-36
  • DOI: 10.2172/674922 | External Link
  • Office of Scientific & Technical Information Report Number: 674922
  • Archival Resource Key: ark:/67531/metadc706920

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  • November 1998

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  • Sept. 12, 2015, 6:31 a.m.

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  • May 5, 2016, 7:23 p.m.

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Frauenfelder, H.; Berendzen, J.R.; Garcia, A.; Gupta, G.; Olah, G. A.; Terwilliger, T. C. et al. Structure, dynamics, and function of biomolecules, report, November 1998; New Mexico. (digital.library.unt.edu/ark:/67531/metadc706920/: accessed August 21, 2017), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT Libraries Government Documents Department.