Initial Experimental Verification of the Neutron Beam Modeling for the LBNL BNCT Facility

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In preparation for future clinical BNCT trials, neutron production via the 7Li(p,n) reaction as well as subsequent moderation to produce epithermal neutrons have been studied. Proper design of a moderator and filter assembly is crucial in producing an optimal epithermal neutron spectrum for brain tumor treatments. Based on in-phantom figures-of-merit,desirable assemblies have been identified. Experiments were performed at the Lawrence Berkeley National Laboratory's 88-inch cyclotron to characterize epithermal neutron beams created using several microampere of 2.5 MeV protons on a lithium target. The neutron moderating assembly consisted of Al/AlF3 and Teflon, with a lead reflector to produce an epithermal spectrum ... continued below

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13 p.

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Bleuel, D.L.; Chu, W.T.; Donahue, R.J.; Ludewigt, B.A.; McDonald, R.J.; Smith, A.R. et al. January 19, 1999.

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In preparation for future clinical BNCT trials, neutron production via the 7Li(p,n) reaction as well as subsequent moderation to produce epithermal neutrons have been studied. Proper design of a moderator and filter assembly is crucial in producing an optimal epithermal neutron spectrum for brain tumor treatments. Based on in-phantom figures-of-merit,desirable assemblies have been identified. Experiments were performed at the Lawrence Berkeley National Laboratory's 88-inch cyclotron to characterize epithermal neutron beams created using several microampere of 2.5 MeV protons on a lithium target. The neutron moderating assembly consisted of Al/AlF3 and Teflon, with a lead reflector to produce an epithermal spectrum strongly peaked at 10-20 keV. The thermal neutron fluence was measured as a function of depth in a cubic lucite head phantom by neutron activation in gold foils. Portions of the neutron spectrum were measured by in-air activation of six cadmium-covered materials (Au, Mn, In, Cu, Co, W) with high epithermal neutron absorption resonances. The results are reasonably reproduced in Monte Carlo computational models, confirming their validity.

Physical Description

13 p.

Notes

INIS; OSTI as DE00006540

Medium: P; Size: 13 pages

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  • The 15th International Conference on the Application of Accelerators in Research and Industry (CAARI), Conference location not supplied, Conference dates not supplied

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  • Report No.: LBNL--42956
  • Grant Number: AC03-76SF00098
  • Office of Scientific & Technical Information Report Number: 6540
  • Archival Resource Key: ark:/67531/metadc705496

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  • January 19, 1999

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  • Sept. 12, 2015, 6:31 a.m.

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  • April 7, 2017, 1:14 p.m.

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Bleuel, D.L.; Chu, W.T.; Donahue, R.J.; Ludewigt, B.A.; McDonald, R.J.; Smith, A.R. et al. Initial Experimental Verification of the Neutron Beam Modeling for the LBNL BNCT Facility, article, January 19, 1999; Berkeley, California. (digital.library.unt.edu/ark:/67531/metadc705496/: accessed September 25, 2017), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT Libraries Government Documents Department.