Scaling model for laser-produced bubbles in soft tissue

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Description

The generation of vapor-driven bubbles is common in many emerging laser-medical therapies involving soft tissues. To successfully apply such bubbles to processes such as tissue break-up and removal, it is critical to understand their physical characteristics. To complement previous experimental and computational studies, an analytic mathematical model for bubble creation and evolution is presented. In this model, the bubble is assumed to be spherically symmetric, and the laser pulse length is taken to be either very short or very long compared to the bubble expansion timescale. The model is based on the Rayleigh cavitation bubble model. In this description, the ... continued below

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11 p.

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London, R. A., LLNL March 12, 1998.

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Description

The generation of vapor-driven bubbles is common in many emerging laser-medical therapies involving soft tissues. To successfully apply such bubbles to processes such as tissue break-up and removal, it is critical to understand their physical characteristics. To complement previous experimental and computational studies, an analytic mathematical model for bubble creation and evolution is presented. In this model, the bubble is assumed to be spherically symmetric, and the laser pulse length is taken to be either very short or very long compared to the bubble expansion timescale. The model is based on the Rayleigh cavitation bubble model. In this description, the exterior medium is assumed to be an infinite incompressible fluid, while the bubble interior consists of a mixed liquid-gas medium which is initially heated by the laser. The heated interior provides the driving pressure which expands the bubble. The interior region is assumed to be adiabatic and is described by the standard water equation-of-state, available in either tabular, or analytic forms. Specifically, we use adiabats from the equation-of-state to describe the evolution of the interior pressure with bubble volume. Analytic scaling laws are presented for the maximum size, the duration, and the energy of bubbles as functions of the laser energy and initially heated volume. Of particular interest, is the efficiency of converting laser energy into bubble motion.

Physical Description

11 p.

Notes

OSTI as DE98058614

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  • BIOS `98: an international symposium on biomedical optics, San Jose, CA (United States), 24-30 Jan 1998

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  • Other: DE98058614
  • Report No.: UCRL-JC--128034
  • Report No.: CONF-980117--
  • Grant Number: W-7405-ENG-48
  • Office of Scientific & Technical Information Report Number: 672327
  • Archival Resource Key: ark:/67531/metadc701936

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Office of Scientific & Technical Information Technical Reports

Reports, articles and other documents harvested from the Office of Scientific and Technical Information.

Office of Scientific and Technical Information (OSTI) is the Department of Energy (DOE) office that collects, preserves, and disseminates DOE-sponsored research and development (R&D) results that are the outcomes of R&D projects or other funded activities at DOE labs and facilities nationwide and grantees at universities and other institutions.

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  • March 12, 1998

Added to The UNT Digital Library

  • Sept. 12, 2015, 6:31 a.m.

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  • May 8, 2017, 12:46 p.m.

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London, R. A., LLNL. Scaling model for laser-produced bubbles in soft tissue, article, March 12, 1998; California. (digital.library.unt.edu/ark:/67531/metadc701936/: accessed June 21, 2018), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT Libraries Government Documents Department.