Applicability of a field-portable toxic heavy metal detector, using a radioisotope-tagged metalloprotein, to DOE environmental remediation and waste minimization initiatives Metadata

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Title

  • Main Title Applicability of a field-portable toxic heavy metal detector, using a radioisotope-tagged metalloprotein, to DOE environmental remediation and waste minimization initiatives

Creator

  • Author: Randles, K.E.
    Creator Type: Personal
    Creator Info: Kansas State Univ., Manhattan, KS (United States)
  • Author: Bragg, D.J.
    Creator Type: Personal
  • Author: Bodette, D.E.
    Creator Type: Personal
  • Author: Lipinski, R.J.
    Creator Type: Personal
  • Author: Luera, T.F.
    Creator Type: Personal
    Creator Info: Sandia National Labs., Albuquerque, NM (United States)

Contributor

  • Sponsor: United States. Department of Energy. Office of Financial Management and Controller.
    Contributor Type: Organization
    Contributor Info: USDOE Office of Financial Management and Controller, Washington, DC (United States)

Publisher

  • Name: Sandia National Laboratories
    Place of Publication: Albuquerque, New Mexico
    Additional Info: Sandia National Labs., Albuquerque, NM (United States)

Date

  • Creation: 1998-08-01

Language

  • English

Description

  • Content Description: A system based on the metal-binding kidney protein, metallothionein, bound with a trace quantity of radioactive metal, has been shown to be capable of detecting parts-per-million (ppm) to parts-per-billion (ppb) concentrations of some heavy metals in liquid solution. The main objective of this study was to determine if this type of system has adequate sensitivity and selectivity for application in detecting a number of metallic species of concern to DOE, such as mercury, lead, and chromium. An affinity-displacement study is reported here using the heavy metal radiotracers {sup 65}Zn and {sup 109}Cd bound to metallothionein immobilized on an Affi-Gel 10 filter support. When a heavy metal solution with a greater affinity than the tracer for the protein is poured through the filter the radiotracer is displaced by a mechanism similar to ion exchange. The main objective of this study was to verify previous internal experimental parameters and results, and to determine the specific affinities of metallothionein for the metallic species of most concern to DOE.
  • Physical Description: 27 p.

Subject

  • Keyword: Metallothionein
  • Keyword: Lead
  • Keyword: Us Doe
  • Keyword: Sensitivity Analysis
  • Keyword: Remedial Action
  • STI Subject Categories: 05 Nuclear Fuels
  • Keyword: Mercury
  • Keyword: Measuring Instruments
  • Keyword: Numerical Data
  • Keyword: Chromium
  • Keyword: Portable Equipment

Source

  • Other Information: PBD: Aug 1998

Collection

  • Name: Office of Scientific & Technical Information Technical Reports
    Code: OSTI

Institution

  • Name: UNT Libraries Government Documents Department
    Code: UNTGD

Resource Type

  • Report

Format

  • Text

Identifier

  • Other: DE98007354
  • Report No.: SAND--97-2367
  • Grant Number: AC04-94AL85000
  • DOI: 10.2172/639710
  • Office of Scientific & Technical Information Report Number: 639710
  • Archival Resource Key: ark:/67531/metadc693357

Note

  • Display Note: INIS; OSTI as DE98007354