Neutronics analysis of three beam-filter assemblies for an accelerator-based BNCT facility

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Three moderator materials, AlF{sub 3}/Al, D{sub 2}O and LiF, have been analyzed for clinical usefulness using the reaction {sup 7}Li(p,n) as an accelerator driven neutron source. Proton energies between 2.1 MeV and 2.6 MeV have been investigated. Radiation transport in the reflector/moderator assembly is simulated using the MCNP program. Depth-dose distributions in a head phanton are calculated with the BNCT-RTPE patient treatment planning program from INEEL using the MCNP generated neutron and photon spectra as the subsequent source. Clinical efficacy is compared using the current BMRR protocol for all designs. Depth-dose distributions are compared for a fixed normal tissue tolerance ... continued below

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14 p.

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Bleuel, D.L.; Costes, S.V.; Donahue, R.J. & Ludewigt, B.A. August 1, 1997.

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Description

Three moderator materials, AlF{sub 3}/Al, D{sub 2}O and LiF, have been analyzed for clinical usefulness using the reaction {sup 7}Li(p,n) as an accelerator driven neutron source. Proton energies between 2.1 MeV and 2.6 MeV have been investigated. Radiation transport in the reflector/moderator assembly is simulated using the MCNP program. Depth-dose distributions in a head phanton are calculated with the BNCT-RTPE patient treatment planning program from INEEL using the MCNP generated neutron and photon spectra as the subsequent source. Clinical efficacy is compared using the current BMRR protocol for all designs. Depth-dose distributions are compared for a fixed normal tissue tolerance dose of 12.5 Gy-Eq. Radiation analyses also include a complete anthropomorphic phantom. Results of organ and whole body dose components are presented for several designs. Results indicate that high quality accelerator beams may produce clinically favorable treatments to deep-seated tumors when compared to the BMRR beam. Also discussed are problems identified in comparing accelerator and reactor based designs using in-air figures of merit as well as some results of spectrum-averaged RBE`s.

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14 p.

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INIS; OSTI as DE97054544

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  • 1997 American Nuclear Society (ANS) winter meeting, Albuquerque, NM (United States), 16-20 Nov 1997

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  • Other: DE97054544
  • Report No.: LBNL--40306
  • Report No.: CONF-971125--
  • Grant Number: AC03-76SF00098
  • Office of Scientific & Technical Information Report Number: 552773
  • Archival Resource Key: ark:/67531/metadc691121

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  • August 1, 1997

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  • Aug. 14, 2015, 8:43 a.m.

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  • April 5, 2016, 10:22 a.m.

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Bleuel, D.L.; Costes, S.V.; Donahue, R.J. & Ludewigt, B.A. Neutronics analysis of three beam-filter assemblies for an accelerator-based BNCT facility, article, August 1, 1997; California. (digital.library.unt.edu/ark:/67531/metadc691121/: accessed September 25, 2017), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT Libraries Government Documents Department.