CT with monochromatic synchrotron x rays and its potential in clinical research

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A monochromatic CT for imaging the human head and neck is being developed at the National Synchrotron Light Source. We compared the performance of this system, multiple energy computed tomography [MECT], with that of a conventional CT [CCT] using phantoms. The advantage in image contrast of MECT, with its beam energy turned just above the K-edge of contrast element, over CCT carried out at 120 kVp, was {approx} 3.2-fold for iodine and {approx} 2.2 fold for gadolinium. Image noise was compared by simulations because this comparison requires matching the spatial resolutions of the two systems. Simulations at a 3-rad dose ... continued below

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9 p.

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Dilmanian, F.A.; Wu, Xiao Ye; Ren, B. & Huang, Xiaoling November 1, 1997.

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Description

A monochromatic CT for imaging the human head and neck is being developed at the National Synchrotron Light Source. We compared the performance of this system, multiple energy computed tomography [MECT], with that of a conventional CT [CCT] using phantoms. The advantage in image contrast of MECT, with its beam energy turned just above the K-edge of contrast element, over CCT carried out at 120 kVp, was {approx} 3.2-fold for iodine and {approx} 2.2 fold for gadolinium. Image noise was compared by simulations because this comparison requires matching the spatial resolutions of the two systems. Simulations at a 3-rad dose and 3-mm slice height on an 18-cm-diameter acrylic phantom, with MECT operating at 60.5 keV, showed that image noise for MECT was 1.4 HU vs. 1.8 HU for CCT. Simulations in the dual energy quantitative CT [DEQCT] mode showed a two-fold advantage for MECT in image noise, as well as its superior quantification. MECT operated in the planar mode revealed fatty tissue in the body of rat using xenon K-edge subtraction. Our initial plan for clinical application of the system is to image the composition of carotid artery plaques non-invasively, separating the plaques` main constituents: the fatty, fibrous, and calcified tissues.

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9 p.

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OSTI as DE98000969

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  • Annual meeting of the Society of Photo-Optical Instrumentation Engineers, San Diego, CA (United States), 27 Jul - 1 Aug 1997

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  • Other: DE98000969
  • Report No.: BNL--64837
  • Report No.: CONF-970706--
  • Grant Number: AC02-76CH00016
  • Office of Scientific & Technical Information Report Number: 544735
  • Archival Resource Key: ark:/67531/metadc690582

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Office of Scientific & Technical Information Technical Reports

Reports, articles and other documents harvested from the Office of Scientific and Technical Information.

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  • November 1, 1997

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  • Aug. 14, 2015, 8:43 a.m.

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  • Nov. 9, 2015, 9:40 p.m.

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Dilmanian, F.A.; Wu, Xiao Ye; Ren, B. & Huang, Xiaoling. CT with monochromatic synchrotron x rays and its potential in clinical research, article, November 1, 1997; Upton, New York. (digital.library.unt.edu/ark:/67531/metadc690582/: accessed November 14, 2018), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT Libraries Government Documents Department.