Doses delivered to normal brain under different treatment protocols at Brookhaven National Laboratory

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As of October 31, 1996, 23 glioblastoma multiforme patients underwent BNCT under several treatment protocols at the Brookhaven Medical Research Reactor. For treatment planning and dosimetry purposes, these protocols may be divided into four groups. The first group comprises protocols that used an 8-cm collimator and allowed a peak normal brain dose of 10.5 Gy-Eq to avolume of 1 cm{sup 3} were the thermal neutron flux was maximal (even if it happened to be in the tumor volume). The second group differs from the first in that it allowed a peak normal brain dose of 12.6 Gy-Eq. The protocols of ... continued below

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9 p.

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Capala, J.; Coderre, J.A. & Liu, H.B. December 31, 1996.

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Description

As of October 31, 1996, 23 glioblastoma multiforme patients underwent BNCT under several treatment protocols at the Brookhaven Medical Research Reactor. For treatment planning and dosimetry purposes, these protocols may be divided into four groups. The first group comprises protocols that used an 8-cm collimator and allowed a peak normal brain dose of 10.5 Gy-Eq to avolume of 1 cm{sup 3} were the thermal neutron flux was maximal (even if it happened to be in the tumor volume). The second group differs from the first in that it allowed a peak normal brain dose of 12.6 Gy-Eq. The protocols of the third and fourth groups allowed the prescribed peak normal brain dose of 12.6 Gy-Eq to be outside of the tumor volume, used a 12-cm collimator and, respectively, uni- or bilateral irradiations. We describe the treatment planning procedures and report the doses delivered to various structures of the brain.

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9 p.

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OSTI as DE97008896

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  • 7. international symposium on neutron capture therapy for cancer, Zurich (Switzerland), 4-7 Sep 1996

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  • Other: DE97008896
  • Report No.: BNL--64622
  • Report No.: CONF-9609293--
  • Grant Number: AC02-76CH00016
  • Office of Scientific & Technical Information Report Number: 539883
  • Archival Resource Key: ark:/67531/metadc689797

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Office of Scientific & Technical Information Technical Reports

Reports, articles and other documents harvested from the Office of Scientific and Technical Information.

Office of Scientific and Technical Information (OSTI) is the Department of Energy (DOE) office that collects, preserves, and disseminates DOE-sponsored research and development (R&D) results that are the outcomes of R&D projects or other funded activities at DOE labs and facilities nationwide and grantees at universities and other institutions.

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  • December 31, 1996

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  • Aug. 14, 2015, 8:43 a.m.

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  • Nov. 6, 2015, 11:46 p.m.

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Capala, J.; Coderre, J.A. & Liu, H.B. Doses delivered to normal brain under different treatment protocols at Brookhaven National Laboratory, article, December 31, 1996; Upton, New York. (digital.library.unt.edu/ark:/67531/metadc689797/: accessed October 20, 2018), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT Libraries Government Documents Department.