Simulation studies of vapor bubble generation by short-pulse lasers

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Formation of vapor bubbles is characteristic of many applications of short-pulse lasers in medicine. An understanding of the dynamics of vapor bubble generation is useful for developing and optimizing laser-based medical therapies. To this end, experiments in vapor bubble generation with laser light deposited in an aqueous dye solution near a fiber-optic tip have been performed. Numerical hydrodynamic simulations have been developed to understand and extrapolate results from these experiments. Comparison of two-dimensional simulations with the experiment shows excellent agreement in tracking the bubble evolution. Another regime of vapor bubble generation is short-pulse laser interactions with melanosomes. Strong shock generation ... continued below

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16 p.

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Amendt, P.; London, R.A. & Strauss, M. October 26, 1997.

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Description

Formation of vapor bubbles is characteristic of many applications of short-pulse lasers in medicine. An understanding of the dynamics of vapor bubble generation is useful for developing and optimizing laser-based medical therapies. To this end, experiments in vapor bubble generation with laser light deposited in an aqueous dye solution near a fiber-optic tip have been performed. Numerical hydrodynamic simulations have been developed to understand and extrapolate results from these experiments. Comparison of two-dimensional simulations with the experiment shows excellent agreement in tracking the bubble evolution. Another regime of vapor bubble generation is short-pulse laser interactions with melanosomes. Strong shock generation and vapor bubble generation are common physical features of this interaction. A novel effect of discrete absorption by melanin granules within a melanosome is studied as a possible role in previously reported high Mach number shocks.

Physical Description

16 p.

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OSTI as DE98051349

Other: FDE: PDF; PL:

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  • BiOS Europe `97, San Femo (Italy), 4-8 Sep 1997

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  • Other: DE98051349
  • Report No.: UCRL-JC--126822
  • Report No.: CONF-9709148--
  • Grant Number: W-7405-ENG-48
  • Office of Scientific & Technical Information Report Number: 328500
  • Archival Resource Key: ark:/67531/metadc677361

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  • October 26, 1997

Added to The UNT Digital Library

  • July 25, 2015, 2:20 a.m.

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  • April 10, 2017, 2:02 p.m.

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Amendt, P.; London, R.A. & Strauss, M. Simulation studies of vapor bubble generation by short-pulse lasers, article, October 26, 1997; California. (digital.library.unt.edu/ark:/67531/metadc677361/: accessed September 21, 2017), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT Libraries Government Documents Department.