Acute skin lesions due to localized ``hot particle`` radiation exposures

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Purpose of the studies was to determine incidence and severity of lesions resulting from localized deposition of dose to the skin from small (<0.5 mm) discrete radioactive particles. Hanford mini-swine were exposed to localized doses from 0.2 to over 600 Gy (averaged over 1 cm{sup 2} at 70{mu}m depth) from isotopes having max beta particle energies from about 0.3-3 MeV. Incidence of erythema and scabs (indicating ulceration) were scored routinely for up to 71 days post-irradiation. Responses followed normal probability distributions, and thus, no true threshold could be defined. Ten and 50% incidence rates were deduced using probit analyses. Lowest ... continued below

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Baum, J.W.; Carsten, A.L.; Kaurin, D.G.L. & Schaefer, C.W. June 1, 1996.

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Purpose of the studies was to determine incidence and severity of lesions resulting from localized deposition of dose to the skin from small (<0.5 mm) discrete radioactive particles. Hanford mini-swine were exposed to localized doses from 0.2 to over 600 Gy (averaged over 1 cm{sup 2} at 70{mu}m depth) from isotopes having max beta particle energies from about 0.3-3 MeV. Incidence of erythema and scabs (indicating ulceration) were scored routinely for up to 71 days post-irradiation. Responses followed normal probability distributions, and thus, no true threshold could be defined. Ten and 50% incidence rates were deduced using probit analyses. Lowest dose producing 10% incidence was about 1 Gy for exposures to Yb-175 (0.5 MeV max energy) beta particles. Severity of lesions was estimated using diameters and persistence. From preliminary considerations of probability of induction, size, and persistence of acute lesions, a special limit for hot particle exposures in the range of 5-50 Gy may be reasonable, with an action level between about 1 Gy and the limit.

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3 p.

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INIS; OSTI as DE96011492

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  • 9. international congress on radiation protection and general assembly of the International Radiation Protection Association (IRPA), Vienna (Austria), 14-19 Apr 1996

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  • Other: DE96011492
  • Report No.: BNL-NUREG--62140
  • Report No.: CONF-960409--4
  • Grant Number: AC02-76CH00016
  • Office of Scientific & Technical Information Report Number: 248698
  • Archival Resource Key: ark:/67531/metadc673343

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Office of Scientific & Technical Information Technical Reports

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  • June 1, 1996

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  • June 29, 2015, 9:42 p.m.

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  • April 7, 2016, 7:31 p.m.

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Baum, J.W.; Carsten, A.L.; Kaurin, D.G.L. & Schaefer, C.W. Acute skin lesions due to localized ``hot particle`` radiation exposures, article, June 1, 1996; Upton, New York. (digital.library.unt.edu/ark:/67531/metadc673343/: accessed November 12, 2018), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT Libraries Government Documents Department.