Comparison of old and new ICRP models for respiratory tract dosimetry

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This paper examines the historical development and application of respiratory tract dosimetry models by the International Commission for Radiological Protection, ICRP, for health protection from inhaled radioactive aerosols. Three different models are discussed, those that were included in ICRP recommendations published in 1960 and 1979, and the new ICRP Publication 66. Basic features of these models are compared and contrasted. These features include model structure, sites and frequencies of particle deposition, processes and rates of clearance of the deposited material from the respiratory tract, and consideration of the parameters involved in these processes and how various factors can influence these ... continued below

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26 p.

Creation Information

Boecker, B.B. December 31, 1993.

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Description

This paper examines the historical development and application of respiratory tract dosimetry models by the International Commission for Radiological Protection, ICRP, for health protection from inhaled radioactive aerosols. Three different models are discussed, those that were included in ICRP recommendations published in 1960 and 1979, and the new ICRP Publication 66. Basic features of these models are compared and contrasted. These features include model structure, sites and frequencies of particle deposition, processes and rates of clearance of the deposited material from the respiratory tract, and consideration of the parameters involved in these processes and how various factors can influence these parameters. All three models lead to the calculation of absorbed radiation doses with differing degrees of regional and local specificity. These calculations are achieved using different tools ranging from quick hand calculations to sophisticated computerized modeling approaches. A side-by-side review of these models indicates several important trends in respiratory tract dosimetry models, the most obvious of which is the increased complexity of each new model over the past 30+ years. These increases reflect both the increasing size of the knowledge base derived from studies in laboratory animals and in human subjects and the need for models more broadly applicable for both occupational and environmental exposures. It is likely that future research will be directed to those key aspects of the new model having the largest uncertainties. The detailed design of the new model and its associated software provide excellent means of identifying useful research areas and using the resulting new information in organized and productive ways.

Physical Description

26 p.

Notes

INIS; OSTI as DE95007673

Source

  • Radiobiology of inhaled radionuclides, Richland, WA (United States), Nov 1993

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  • Other: DE95007673
  • Report No.: CONF-9311220--1
  • Grant Number: AC04-76EV01013
  • DOI: 10.2172/28286 | External Link
  • Office of Scientific & Technical Information Report Number: 28286
  • Archival Resource Key: ark:/67531/metadc668503

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Office of Scientific & Technical Information Technical Reports

Reports, articles and other documents harvested from the Office of Scientific and Technical Information.

Office of Scientific and Technical Information (OSTI) is the Department of Energy (DOE) office that collects, preserves, and disseminates DOE-sponsored research and development (R&D) results that are the outcomes of R&D projects or other funded activities at DOE labs and facilities nationwide and grantees at universities and other institutions.

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  • December 31, 1993

Added to The UNT Digital Library

  • June 29, 2015, 9:42 p.m.

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  • Nov. 19, 2015, 4:20 p.m.

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Boecker, B.B. Comparison of old and new ICRP models for respiratory tract dosimetry, report, December 31, 1993; United States. (digital.library.unt.edu/ark:/67531/metadc668503/: accessed January 22, 2018), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT Libraries Government Documents Department.