Peregrine monte carlo dose calculations for radiotherapy using clinically realistic neutron and proton beams

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Lawrence Livermore National Laboratory (LLNL) has developed an all-particle Monte Carlo radiotherapy dose calculation code--PEREGRINE--for use in clinical radiation oncology. For PEREGRINE, we have assembled high-energy evaluated nuclear databases; created radiation source characterization and sampling algorithms; and simulated and characterized clinical beams for treatment with photons, neutrons and protons. Spectra are available for the Harper Hospital (Detroit, U.S.A.) Be(d,n) neutron therapy beam, the National Accelerator Centre (NAC, Faure, S.A.) Be(p,n) neutron therapy beam and many of the operating modes of the Loma Linda University Medical Center (LLUMC, Loma Linda, USA) proton treatment center. These beam descriptions are being used in ... continued below

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10 pages; Other: FDE: PDF

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Cox, L. J., LLNL June 16, 1997.

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Description

Lawrence Livermore National Laboratory (LLNL) has developed an all-particle Monte Carlo radiotherapy dose calculation code--PEREGRINE--for use in clinical radiation oncology. For PEREGRINE, we have assembled high-energy evaluated nuclear databases; created radiation source characterization and sampling algorithms; and simulated and characterized clinical beams for treatment with photons, neutrons and protons. Spectra are available for the Harper Hospital (Detroit, U.S.A.) Be(d,n) neutron therapy beam, the National Accelerator Centre (NAC, Faure, S.A.) Be(p,n) neutron therapy beam and many of the operating modes of the Loma Linda University Medical Center (LLUMC, Loma Linda, USA) proton treatment center. These beam descriptions are being used in PEREGRINE for Monte Carlo dose calculations on clinical configurations for comparisons to measurements. The methods of defining and sampling the beam phase space characterizations are discussed. We show calculations using these clinical beams compared to measurements in homogeneous water phantoms. The state of PEREGRINE's high energy neutron and proton transport database, PCSL, is reviewed and the remaining issues involving nuclear data needs for PEREGRINE are addressed.

Physical Description

10 pages; Other: FDE: PDF

Notes

OSTI as DE00016385

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  • International Conference on Nuclear Data for Science and Technology, Trieste (IT), 05/19/1997--05/21/1997; Other Information: Supercedes report DE98051004; PBD: 16 Jun 97

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  • Other: DE98051004
  • Report No.: UCRL-JC-127198
  • Report No.: CONF-9705133--
  • Grant Number: W-7405-Eng-48
  • Office of Scientific & Technical Information Report Number: 16385
  • Archival Resource Key: ark:/67531/metadc627954

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Reports, articles and other documents harvested from the Office of Scientific and Technical Information.

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  • June 16, 1997

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  • June 16, 2015, 7:43 a.m.

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  • Jan. 3, 2017, 1:08 p.m.

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Cox, L. J., LLNL. Peregrine monte carlo dose calculations for radiotherapy using clinically realistic neutron and proton beams, article, June 16, 1997; (digital.library.unt.edu/ark:/67531/metadc627954/: accessed December 15, 2017), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT Libraries Government Documents Department.