Sol gel based fiber optic sensor for blook pH measurement

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Description

This paper describes a fiber-optic pH sensor based upon sol-gel encapsulation of a self-referencing dye, seminaphthorhodamine-1 carboxylate (SNARF-1C). The simple sol-gel fabrication procedure and low coating leachability are ideal for encapsulation and immobilization of dye molecules onto the end of an optical fiber. A miniature bench-top fluorimeter system was developed for use with the optical fiber to obtain pH measurements. Linear and reproducible responses were obtained in human blood in the pH range 6.8 to 8.0, which encompasses the clinically-relevant range. Therefore, this sensor can be considered for in vivo use.

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20 pages

Creation Information

Grant, S. A. & Glass, R. S. December 19, 1996.

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Description

This paper describes a fiber-optic pH sensor based upon sol-gel encapsulation of a self-referencing dye, seminaphthorhodamine-1 carboxylate (SNARF-1C). The simple sol-gel fabrication procedure and low coating leachability are ideal for encapsulation and immobilization of dye molecules onto the end of an optical fiber. A miniature bench-top fluorimeter system was developed for use with the optical fiber to obtain pH measurements. Linear and reproducible responses were obtained in human blood in the pH range 6.8 to 8.0, which encompasses the clinically-relevant range. Therefore, this sensor can be considered for in vivo use.

Physical Description

20 pages

Notes

INIS; OSTI as DE00016192

Source

  • Photonics West, San Jose, CA (US), 02/08/1997--02/14/1997; Other Information: Supercedes report DE97053923

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  • Other: DE97053923
  • Report No.: UCRL-JC-125297
  • Grant Number: W-7405-Eng-48
  • Office of Scientific & Technical Information Report Number: 16192
  • Archival Resource Key: ark:/67531/metadc618280

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Office of Scientific & Technical Information Technical Reports

Reports, articles and other documents harvested from the Office of Scientific and Technical Information.

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  • December 19, 1996

Added to The UNT Digital Library

  • June 16, 2015, 7:43 a.m.

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  • May 6, 2016, 2:02 p.m.

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Grant, S. A. & Glass, R. S. Sol gel based fiber optic sensor for blook pH measurement, article, December 19, 1996; Livermore, California. (digital.library.unt.edu/ark:/67531/metadc618280/: accessed November 19, 2017), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT Libraries Government Documents Department.