Modeling the Impact and Intervention of a Sexually Transmitted Disease: Human Papilloma Virus

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Description

Many human papilloma virus (HPV) types are sexually transmitted and HPV DNA types 16, 18, 31, and 45 account for more than 75% if all cervical dysplasia. Candidate vaccines are successfully completing US Federal Drug Agency (FDA) phase III testing and several drug companies are in licensing arbitration. Once this vaccine become available it is unlikely that 100% vaccination coverage will be probable; hence, the need for vaccination strategies that will have the greatest reduction on the endemic prevalence of HPV. This thesis introduces two discrete-time models for evaluating the effect of demographic-biased vaccination strategies: one model incorporates temporal demographics ... continued below

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Corley, Courtney D. May 2006.

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This thesis is part of the collection entitled: UNT Theses and Dissertations and was provided by UNT Libraries to Digital Library, a digital repository hosted by the UNT Libraries. It has been viewed 321 times . More information about this thesis can be viewed below.

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  • Corley, Courtney D.

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Many human papilloma virus (HPV) types are sexually transmitted and HPV DNA types 16, 18, 31, and 45 account for more than 75% if all cervical dysplasia. Candidate vaccines are successfully completing US Federal Drug Agency (FDA) phase III testing and several drug companies are in licensing arbitration. Once this vaccine become available it is unlikely that 100% vaccination coverage will be probable; hence, the need for vaccination strategies that will have the greatest reduction on the endemic prevalence of HPV. This thesis introduces two discrete-time models for evaluating the effect of demographic-biased vaccination strategies: one model incorporates temporal demographics (i.e., age) in population compartments; the other non-temporal demographics (i.e., race, ethnicity). Also presented is an intuitive Web-based interface that was developed to allow the user to evaluate the effects on prevalence of a demographic-biased intervention by tailoring the model parameters to specific demographics and geographical region.

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  • May 2006

Added to The UNT Digital Library

  • May 5, 2008, 2:03 p.m.

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  • Jan. 21, 2014, 1:50 p.m.

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Citations, Rights, Re-Use

Corley, Courtney D. Modeling the Impact and Intervention of a Sexually Transmitted Disease: Human Papilloma Virus, thesis, May 2006; Denton, Texas. (digital.library.unt.edu/ark:/67531/metadc5289/: accessed October 19, 2017), University of North Texas Libraries, Digital Library, digital.library.unt.edu; .