Experiment Station Record, Volume 92, January-June, 1945 Page: 113
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1945] VETERINARY MEDICINE 113
"Cattle up to 2% yr. of age can be sensitized by the subcutaneous inoculation of
10-mg. strains of M[ycobacterium] butyricum and M. phlei suspended in liquid
paraffin. Larger amounts of the organisms do not appear to give rise to a greater
degree of sensitivity. Cattle sensitized by subcutaneous inoculation of strains of
M. butyricum and M. phlei gave definite suspicious reactions when tested with
tuberculin by the double intradermal method. .These same animals when tested with
avian tuberculin showed no more marked suspicious reactions than when tested
with standard tuberculin. Thirteen and a half months after subcutaneous inoculation
with strains of M. butyricum the nonpathogenic organism M. butyricum could
be cultivated from pus obtained from the resultant lesion. Sections cut from the
lesions set up by these two organisms showed changes indistinguishable from those
set up by tuberculosis. Four months after the surgical removal of the lesions set
up by the inoculation of the nonpathogenic acid-fast organisms, the animals still
gave definite positive reactions when tested against the corresponding extracts. It
is probable that some nonspecific reactions shown by animals, when tested with
tuberculin, may be due to these animals being sensitized naturally by a strain or
strains of some nonpathogenic acid-fast organism. This may also be an explanation
for some of the 'no lesion' reactors to the double intradermal tuberculin test."
There are 83 literature citations.
Bibliography of phenothiazine as an anthelmintic, R. T. LEIPER (St. Albans,
Eng.: Imp. Bur. Parasitol. (Helminthol.), 1942, pp. 6+).-This bibliography includes
120 papers received between 1938 and June 1942. Technical papers on the
chemistry of phenothiazine and its insecticidal or fungicidal uses are not included.
Evaluation of disinfectants, W. L. MALLMAN. , (Mich. State Col.). (Soap and
Sanit. Chen., 20 (1944), No. 8, pp. 101, 119, 121, 123, 131, illus. 2).-This is
mainly a discussion of methods, especially the phenol coefficient. This is regarded
as useful in aiding in the selection of ingredients and as a check on the resulting
mixture for stability, but the final analysis, it is maintained, should be a use test.
"A standard use test should be developed."
Some aspects of the toxicology of hydrocyanic acid in ruminants, S. J. VAN
DER WALT (Onderstepoort Jour. Vet. Sci. and Atnim. Indus., 19 (1944), No. 1-2,
tp. 79-160, illus. 6).-This thesis discusses the quantitative determination of HCN
in biological material, sources of HCN, factors concerned in the causation of HCN
poisoning, and the ICN. content of the organs of normal animals and animals
poisoned by HCN. Among the conclusions drawn are the following:
"The aeration procedure is the most suitable for the liberation of HCN from
biological material. The ferric thiocyanate method, as modified by the author, is
an accurate and sensitive method in biological material. In the case of certain
plants erroneous results were obtained by the alkaline titration method . . . The
HCN content of cyanogenetic plants varies greatly, one of the most important
factors, responsible for the variation, being climatic conditions. Wilting is responsible
for a great increase ...
"The danger of a cyanogenetic plant to stock should be assessed on the maximum
quantity of HCN which the plant may develop. Under field conditions HCN in
relatively large quantities was frequently demonstrable in the ruminal contents of
animals which had died from causes other than HCN poisoning. Under laboratory
conditions ruminal contents and liver of such animals, on a practically noncyanogenetic
diet, contained only traces of HCN.
"In sheep poisoned by HCN per os the ruminal contents and liver show the
highest concentration of HCN of the organs analyzed. The quantity of HCN
ingested is reflected in the HCN content of the ruminal contents and liver. Since
the presence of HCN in the ruminal contents does not prove that a lethal quantity
of HCN was absorbed, a definite diagnosis cannot be made on the HCN content
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U.S. Department of Agriculture. Agricultural Research Administration. Office of Experiment Stations. Experiment Station Record, Volume 92, January-June, 1945, book, 1947; Washington D.C.. (digital.library.unt.edu/ark:/67531/metadc5064/m1/126/: accessed December 9, 2018), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT Libraries Government Documents Department.