Mutagenic Potential of Tetramethylthiuram Disulfide (42-S Thiram) on the Germ Cell Stages of Drosophila melanogaster

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Tetramethylthiuram disulfide (42-S Thiram), a carbamate fungicide was studied for its mutagenic potential on the germ cell stages of wild-type male Drosophila melanogaster. The mutagenicity was tested using the sex-linked recessive lethal assay (SLRL). Any lethals induced in the F2 generation were evidenced by the absence of wild-type males. Although there was an increase in mutation rates in the 42-S Thiram treated wild-type males over the control wild-type males, it was not significantly higher. According to the laboratory conditions in this preliminary study, tetramethylthiuram disulfide failed to produce mutagenic effect.

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v, 49 leaves : ill.

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Lowe-Chatham, Janice E. (Janice Elaine) December 1990.

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  • Lowe-Chatham, Janice E. (Janice Elaine)

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Tetramethylthiuram disulfide (42-S Thiram), a carbamate fungicide was studied for its mutagenic potential on the germ cell stages of wild-type male Drosophila melanogaster. The mutagenicity was tested using the sex-linked recessive lethal assay (SLRL). Any lethals induced in the F2 generation were evidenced by the absence of wild-type males. Although there was an increase in mutation rates in the 42-S Thiram treated wild-type males over the control wild-type males, it was not significantly higher. According to the laboratory conditions in this preliminary study, tetramethylthiuram disulfide failed to produce mutagenic effect.

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v, 49 leaves : ill.

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  • December 1990

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  • March 9, 2015, 8:15 a.m.

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  • Oct. 9, 2017, 10:42 a.m.

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Lowe-Chatham, Janice E. (Janice Elaine). Mutagenic Potential of Tetramethylthiuram Disulfide (42-S Thiram) on the Germ Cell Stages of Drosophila melanogaster, thesis, December 1990; Denton, Texas. (digital.library.unt.edu/ark:/67531/metadc500794/: accessed September 18, 2018), University of North Texas Libraries, Digital Library, digital.library.unt.edu; .