Legume Natural Products: Understanding and Manipulating Complex Pathways for Human and Animal Health

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Article on legume natural products and understanding and manipulating complex pathways for human and animal health.

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8 p.

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Dixon, R. A. & Sumner, Lloyd W. March 2003.

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Article on legume natural products and understanding and manipulating complex pathways for human and animal health.

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8 p.

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Abstract: "To every thing there is a season” (Ecclesiastes, 3), and interest in plant natural products is certainly undergoing a renaissance at the present time. This is particularly true in the case of the natural products of the Leguminosae, which have long been studied as important taxonomic markers for this complex and economically important family (Wink and Waterman, 1999). In the face of the vast number of natural products collectively produced by plants, the study of specific pathways had been viewed as somewhat esoteric, and attempts to obtain a more global understanding of natural product biosynthesis seemed beyond easy grasp. Those views have been changing in recent years due to the realization of the importance of natural products for plant, animal, and human health, and the impact of genomics technologies on all areas of biology. At least 25% of the genome of Arabidopsis encodes enzymes of metabolism, and the number may be similar or even higher in legumes, several of which now have extensive genomics resources (Quackenbush et al., 2000; Bell et al., 2001). Whole genome-level DNA sequence information, coupled with improved methods for profiling natural products, now make possible combined genetic and biochemical approaches for addressing natural product function, deciphering biosynthetic pathways, and engineering novel pathways in transgenic plants. Several of the following case studies highlight these approaches.

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Copyright 2003 American Society of Plant Biologists. The following article appeared in Plant Physiology, 131:3, pp. 878-885, http:/​/​dx.​doi.​org/​10.​1104/​pp.​102.​017319

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  • Plant Physiology, 2003, Rockville: American Society of Plant Biologists, pp. 878-885

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  • Publication Title: Plant Physiology
  • Volume: 131
  • Issue: 3
  • Page Start: 878
  • Page End: 885
  • Pages: 8
  • Peer Reviewed: Yes

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Materials from the UNT community's research, creative, and scholarly activities and UNT's Open Access Repository. Access to some items in this collection may be restricted.

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  • March 2003

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  • Jan. 22, 2015, 9:04 a.m.

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Dixon, R. A. & Sumner, Lloyd W. Legume Natural Products: Understanding and Manipulating Complex Pathways for Human and Animal Health, article, March 2003; [Rockville, Maryland]. (digital.library.unt.edu/ark:/67531/metadc488148/: accessed May 21, 2018), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT College of Arts and Sciences.