Prediction of drug solubility in ethanol-ethyl acetate mixtures at various temperatures using the Jouyban-Acree model

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Article on the prediction of drug solubility in ethanol-ethyl acetate mixtures at various temperatures using the Jouyban-Acree model.

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2 p.

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Jouyban, Abolghasem & Acree, William E. (William Eugene) 2007.

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This article is part of the collection entitled: UNT Scholarly Works and was provided by UNT College of Arts and Sciences to Digital Library, a digital repository hosted by the UNT Libraries. It has been viewed 64 times . More information about this article can be viewed below.

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  • SciTechnol
    Place of Publication: [Henderson, Nevada]

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Article on the prediction of drug solubility in ethanol-ethyl acetate mixtures at various temperatures using the Jouyban-Acree model.

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2 p.

Notes

Abstract: The profile of twenty-six solubility data sets in ethanol-ethyl acetate mixtures at various temperatures were reproduced using a trained version of the Jouyban-Acree model. The mean percentage deviation between predicted and observed solubilities was 13.1%. The maximum solubility (logX m,max ) in the mixed solvent system and the corresponding solvent composition (f 1,max ) were also predicted by the model. The overall average error of log Xm,max was 0.07 ± 0.04 in logarithmic scale and for f 1,max was 0.07 ± 0.07, which is equal to 7% when solvent composition is expressed as volume percentage of the cosolvent.

Source

  • Journal of Drug Delivery Science and Technology, 2007, Henderson: SciTechnol, pp. 159-160

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Publication Information

  • Publication Title: Journal of Drug Delivery Science and Technology
  • Volume: 17
  • Issue: 2
  • Page Start: 159
  • Page End: 160
  • Peer Reviewed: Yes

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UNT Scholarly Works

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  • 2007

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  • Oct. 23, 2014, 12:02 p.m.

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Jouyban, Abolghasem & Acree, William E. (William Eugene). Prediction of drug solubility in ethanol-ethyl acetate mixtures at various temperatures using the Jouyban-Acree model, article, 2007; [Henderson, Nevada]. (digital.library.unt.edu/ark:/67531/metadc406346/: accessed October 21, 2017), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT College of Arts and Sciences.