Multinetwork Nerve Cell Assay Platform with Parallel Recording Capability Metadata

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  • Main Title Multinetwork Nerve Cell Assay Platform with Parallel Recording Capability


  • Inventor: Gross, Guenter W.
    Creator Type: Personal
    Creator Info: University of North Texas


  • Assignee: University of North Texas
    Contributor Type: Organization


  • Name: United States. Patent Office
    Place of Publication: [Washington, D.C.]


  • Submission Date: 2007-09-12
  • Acceptance Date: 2013-06-11
  • Creation: 2013-06-11


  • English


  • Content Description: Patent relating to a multinetwork nerve cell assay platform with parallel recording capability.
  • Physical Description: 9 p. : ill.


  • Library of Congress Subject Headings: Patents -- Texas.
  • Keyword: neuronal networks
  • Keyword: cell cultures
  • Keyword: parallel recording


  • Place Name: United States - Texas - Denton County - Denton


  • Name: UNT Scholarly Works
    Code: UNTSW


  • Name: UNT College of Arts and Sciences
    Code: UNTCAS


  • Rights Access: public
  • Rights License: pd

Resource Type

  • Patent


  • Text


  • Patent Number: 8460921
  • Government Documents No.: 12/441703
  • Government Documents No.: PCT/US2007/019780
  • Archival Resource Key: ark:/67531/metadc306940


  • Academic Department: Biological Sciences


  • Display Note: Abstract: A neuronal network analysis plate having alternating rows of recording wells and amplifying wells. The recording wells contain a neural cell network and a series of electrodes for recording the action potential signals of the neurons. The electrodes are connected to amplifiers in adjacent amplifying wells. The close proximity of these amplifiers ideal because it permits the parallel, non-multiplexed recording of action potential signals from multiple different active nerve cell networks. The amplifiers in the amplifying wells can then be connected to external amplification equipment. The neuronal network analysis plate may be contained within a single commercially available 24 or 96 well plate. The neuronal network analysis plate can be used to detect and quantify pharmacological and toxicological responses of the neural cells to one or more agents in vitro.
  • Display Note: Prior Publication Data: US 2009/0291466 A1, November 26, 2009.
  • Display Note: Related U.S. Application Data: Provisional application number 60/845399, filed on September 18, 2006.