Process for Synthesizing Oil and Surfactant-free Hyaluronic Acid Nanoparticles and Microparticles

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Description

Patent relating to a process for synthesizing oil and surfactant-free hyaluronic acid nanoparticles and microparticles.

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13 p. : ill.

Creation Information

Hu, Zhibing; Xia, Xiaohu & Tang, Liping October 13, 2009.

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This patent is part of the collection entitled: UNT Scholarly Works and was provided by UNT College of Arts and Sciences to Digital Library, a digital repository hosted by the UNT Libraries. It has been viewed 366 times, with 11 in the last month. More information about this patent can be viewed below.

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Description

Patent relating to a process for synthesizing oil and surfactant-free hyaluronic acid nanoparticles and microparticles.

Physical Description

13 p. : ill.

Notes

Abstract: A method for synthesizing uniformly sized hyaluronic acid (“HA”) particles that are substantially free from oil and surfactant contaminants. The method comprises crosslinking HA chains with 1-ethyl-3-(3-dimethlyaminopropyl) carbodiimide hydrochloride (“EDAC”) and adipic acid dihydrazide in a water/acetone mixture.

Prior Publication Data: US 2006/0040892 A1, February 23, 2006.

Related U.S. Application Data: Provisional application number 60/516,707, filed on November 3, 2003.

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UNT Scholarly Works

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Submitted Date

  • November 3, 2004

Accepted Date

  • October 13, 2009

Creation Date

  • October 13, 2009

Added to The UNT Digital Library

  • July 7, 2014, 8:20 a.m.

Description Last Updated

  • Dec. 12, 2017, 8:21 p.m.

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Hu, Zhibing; Xia, Xiaohu & Tang, Liping. Process for Synthesizing Oil and Surfactant-free Hyaluronic Acid Nanoparticles and Microparticles, patent, October 13, 2009; [Washington, D.C.]. (https://digital.library.unt.edu/ark:/67531/metadc306033/: accessed August 24, 2019), University of North Texas Libraries, Digital Library, https://digital.library.unt.edu; crediting UNT College of Arts and Sciences.