GABAᴀ Receptors in Rat Whisker Barrel Cortex: Effects of Sensory Deprivation

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Description

The GABAergic system in adult sensory cortex is affected by sensory deprivation, but little is known about how this predominant inhibitory system is affected during ontogeny. The present study investigates developmental effects of whisker trimming on GABAa receptors in rat barrel cortex. Rats trimmed for 6 wk beginning at birth and adulthood showed similar decreases in [3H]muscimol binding in deprived relative to non-deprived barrels, suggesting absence of a critical period.

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iv, 23 leaves: ill.

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Salazar, Eduardo, 1962- August 1995.

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  • Salazar, Eduardo, 1962-

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The GABAergic system in adult sensory cortex is affected by sensory deprivation, but little is known about how this predominant inhibitory system is affected during ontogeny. The present study investigates developmental effects of whisker trimming on GABAa receptors in rat barrel cortex. Rats trimmed for 6 wk beginning at birth and adulthood showed similar decreases in [3H]muscimol binding in deprived relative to non-deprived barrels, suggesting absence of a critical period.

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iv, 23 leaves: ill.

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  • August 1995

Added to The UNT Digital Library

  • March 26, 2014, 9:30 a.m.

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  • July 9, 2014, 9:30 a.m.

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Salazar, Eduardo, 1962-. GABAᴀ Receptors in Rat Whisker Barrel Cortex: Effects of Sensory Deprivation, thesis, August 1995; Denton, Texas. (digital.library.unt.edu/ark:/67531/metadc279232/: accessed December 9, 2018), University of North Texas Libraries, Digital Library, digital.library.unt.edu; .