Depression and Heart Rate Variability in Patients with Coronary Artery Disease Metadata

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  • Main Title Depression and Heart Rate Variability in Patients with Coronary Artery Disease


  • Author: Saunders, Roger D. (Roger Dean)
    Creator Type: Personal


  • Chair: Guarnaccia, Charles Anthony
    Contributor Type: Personal
    Contributor Info: Major Professor
  • Committee Member: Kelly, Kimberly
    Contributor Type: Personal
  • Committee Member: Rogers, Richard, 1950-
    Contributor Type: Personal
  • Committee Member: Keller, M. Jean
    Contributor Type: Personal


  • Name: University of North Texas
    Place of Publication: Denton, Texas


  • Creation: 1994-12


  • English


  • Content Description: Depression is an independent risk factor for morbidity and mortality in patients with coronary artery disease (CAD). Altered autonomic nervous system (ANS) activity, a common feature of depression, is also a risk factor for cardiac events in patients with CAD. Heart rate variability (HRV) reflects ANS activity, and reduced HRV predicts morbidity in cardiac populations. The purpose of this study was to determine whether differences in HRV exist between depressed and nondepressed patients with CAD. Twenty-one depressed inpatients, with angiographically documented CAD were retrospectively matched to 21 nondepressed CAD patients by sex, age, and smoking status. Demographic, medical, psychological interview data, and 24-hour ECG recordings were obtained. Depressed subjects had significantly lower HRV, or trends toward lower HRV, than nondepressed subjects, even after controlling for severity of CAD. Subject groups did not differ on left ventricular ejection fraction, history of myocardial infarction, or any other relevant medical variable assessed. These results suggest that depression is associated with decreased HRV in patients with CAD, and may help to explain the increased rates of cardiac events observed in CAD patients with depression.
  • Physical Description: iv, 81 leaves


  • Keyword: depression
  • Keyword: coronary artery disease
  • Keyword: heart rate
  • Library of Congress Subject Headings: Coronary heart disease.
  • Library of Congress Subject Headings: Depression, Mental.
  • Library of Congress Subject Headings: Heart beat.


  • Place Name: United States - Missouri - Saint Louis Independent City - Saint Louis


  • Name: UNT Theses and Dissertations
    Code: UNTETD


  • Name: UNT Libraries
    Code: UNT


  • Rights Access: public
  • Rights License: copyright
  • Rights Statement: Copyright is held by the author, unless otherwise noted. All rights reserved.
  • Rights Holder: Saunders, Roger D. (Roger Dean)

Resource Type

  • Thesis or Dissertation


  • Text


  • Call Number: 379 N81d no.4112
  • UNT Catalog No.: b1854267
  • Accession or Local Control No: 1002720099-saunders
  • Archival Resource Key: ark:/67531/metadc278101


  • Degree Level: Doctoral
  • Degree Grantor: University of North Texas
  • Degree Name: Doctor of Philosophy
  • Academic Department: Department of Psychology
  • Degree Discipline: Clinical Psychology