Blood Pressure Regulation During Simulated Orthostatism Prior to and Following Endurance Exercise Training Page: 3
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Stevens, Glen, H. J., Blood Pressure Regulation During
Simulated Orthostatism Prior to and Following Endurance
Exercise Training. Doctor of Philosophy (Biology), May,
1992, 151 pp., 5 tables, 20 illustrations, bibliography,239
Cardiovascular responses and tolerance to an
orthostatic stress were examined in eight men before and
after eight months of endurance exercise training.
Orthostatic stress was induced using progressive lower body
negative pressure (LBNP) at -5, -15, -25, -35, and -45 torr,
followed by -5 torr increments until presyncope. In
addition, cardiac autonomic blockade was utilized during
LBNP to -45 torr. Cardiopulmonary baroresponsiveness was
assessed as the slope of the relationship between forearm
vascular resistance (FVR) and central venous pressure (CVP)
(utilizing the dependent arm technique) during LBNP < -25
torr. Baroreflex function was further evaluated using
progressive intravenous infusion of phenylephrine
hydrochloride (PE) to a maximum dose of 0.12 mg^min^.
Following training, maximal oxygen consumption and blood
volume were increased, and resting heart rate reduced.
Orthostatic tolerance was reduced following training in all
eight subjects. Blockade of the parasympathetic cardiac
receptors with atropine sulphate resulted in the maintenance
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Stevens, Glen Harold John. Blood Pressure Regulation During Simulated Orthostatism Prior to and Following Endurance Exercise Training, dissertation, May 1992; Denton, Texas. (digital.library.unt.edu/ark:/67531/metadc277914/m1/3/: accessed November 21, 2018), University of North Texas Libraries, Digital Library, digital.library.unt.edu; .